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Biomedical subjects

N E Makhson

Publications and source records attributed to N E Makhson.

At least 19 recordsLinked to original sources
PubMed1990

[Antibacterial chemotherapy in anaerobic osteomyelitis caused by gunshot wounds].

Thirty three patients with a 7-year history of chronic gunshot osteomyelitis were examined. Non-sporogenic anaerobes were isolated from 28 patients. Gram-positive cocci and gram-negative rods predominated in the anaerobic microflora. Radical surgical interventions combined with adequate antibacterial chemotherapy yielded satisfactory results. The postoperative cavities were drained to provide aerobic conditions in all the parts. Antibacterial drugs and in particular dioxidine solutions and KF were used locally. When antibioticograms were available 7 to 10 days after, the antibiotics in combination with enzymes such as terrylitin and lidase were used with constant irrigation of wounds with furacillin or boric acid solutions. In the empirical therapy, the following scheme was most frequently used: 600 mg of lincomycin, thrice, intramuscularly; 80 mg of gentamicin, thrice, intramuscularly and as an obligatory agent 500 mg of trichopol, thrice, orally. After availability of the antibioticograms the use of the antibiotics was adjusted and continued up to 10 to 12 days. In severe cases 0.1% solution of dioxidine was used intravenously drop-wise in a dose of 300 mg 2 times a day as well as tiberal or clindamycin, intravenously, drop-wise. The antibacterial drugs were added to the drainage until the latter was removed. Relapses of the disease over 4 years were observed only in 3 out of 26 operated patients.

Adult↗
PubMed1989

[Diagnostic errors in hematogenic osteomyelitis of the pelvic bones].

The authors have analysed the caused of frequent diagnostic errors in the primary diagnosis which reach 51.2% in 41 patients with hematogenic osteomyelitis of the pelvis. A high percentage of diagnostic errors is caused by more frequent occurrence of hematogenic osteomyelitis of the pelvis in the adults aged 20 to 60 and older who are "not expected" to have hematogenic osteomyelitis which is considered to be a disease characteristic of children and adolescents, by an inadequacy between the provoking etiologic factor and the subsequent development of the disease and by disguise of hematogenic osteomyelitis of the pelvis with symptoms of other frequently occurring diseases. The character of the diagnostic errors is clearly linked with the localization of the process in the bones of the pelvis.

Adult↗
PubMed1986

[Free bone and skin-bone autoplasty on a vascular pedicle in patients with defects and pseudarthroses].

Radical sequestr- and necrectomy followed by skin, bone or skin-bone autoplasty on the vascular pedicle with microvascular anastomoses between the autotransplant vessels and those of the extremity was successfully fulfilled in 16 patients with defects of tubular bones and false joints complicated by chronic osteomyelitis. The pedicled autografts were taken from the upper flaring portion of the ilium (13), from the fibula (2) and from the external surface of the femur (1). The two-step method of autoplasty is described.

Adult↗
PubMed1984

[Radical organ-saving operations in scapular tumors].

The paper deals with analysis of data on 37 cases of scapular neoplasms who had undergone such radical function--saving surgery as interscapular-thoracic resection ( Tikhov - Linberg 's operation) (27) or scapulectomy (10). Modifications of both procedures developed by the authors are described. Their application was followed by an improved functional status as compared with other surgical procedures. Oncological status of 30 cases of primary scapular malignancies is discussed: 23 patients were recurrence- and metastasis-free during a follow-up period of 10 months-18 years (21 patients were operated on more than 5 years ago).

Adolescent↗