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Biomedical subjects

N E Stratas

Publications and source records attributed to N E Stratas.

12 recordsLinked to original sources

Chronic neck and shoulder pain. Focusing on myofascial origins.

Chronic neck and shoulder pain is a complex, multifactorial problem. Often many months have passed since its onset. During this time the patient may have seen many physicians and tried many medications, some with abuse potential. Most patients are depressed and have lost their ability to cope with the stresses of daily life. The goals of therapy are to enable patients to deal with the problem and to bring them to the point where pain is no longer the dominant factor in their lives. For patients with chronic neck and shoulder pain of myofascial origin, this is accomplished with a multi-disciplinary approach that incorporates use of psychotherapeutic techniques, nonsteroidal antiinflammatory medications, antidepressant drugs, trigger-point injection, and several physical therapy modalities.

Chronic Disease↗

A double-blind study of the efficacy and safety of dothiepin hydrochloride in the treatment of major depressive disorder.

In a 6-week double-blind parallel treatment study, dothiepin and amitriptyline were compared to placebo in the treatment of 33 depressed outpatients. Dothiepin and amitriptyline were equally effective in alleviating the symptoms of depressive illness, and both were significantly superior to placebo. The overall incidence of side effects and the frequency and severity of blurred vision, dry mouth, and drowsiness were significantly less with dothiepin than with amitriptyline. Dothiepin also produced fewer CNS and cardiovascular effects. There were no clinically important changes in laboratory parameters. Dothiepin thus was found to be an effective antidepressant drug associated with fewer side effects than amitriptyline in the treatment of depressed outpatients.

Ambulatory Care↗

The future of the mental hospital: developing a unified system of care.

The authors emphasize that the future of state mental hospitals should be considered only in the context of a unified system of care and treatment of the mentally ill. They discuss changing perceptions of mental hospitals as resources for mental health care, describe trends that must be considered in developing a unified system of services, and make recommendations about treatment plans, staffing, funding, organization and governance, and legal codes and standards of the components of a unified system.

Adult↗