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Biomedical subjects

N Ebbehøj

Publications and source records attributed to N Ebbehøj.

28 records · Page 2Linked to original sources
PubMed1989

Pancreaticogastrostomy for chronic pancreatitis.

Forty-five patients with painful chronic pancreatitis underwent side-to-side pancreaticogastrostomy. Correct diagnosis was ensured by endoscopic retrograde cholangiopancreatography, decreased exocrine pancreatic secretion, abdominal calcifications, and histologic verification. A main etiologic factor was alcohol abuse (84 percent of patients). At a median follow-up period of 3.8 years, good, fair, and poor results were achieved in 56, 23, and 21 percent of patients, respectively. The operative mortality rate was 4.4 percent. At follow-up, 16 of the patients were employed, weight was increased by a mean of 2.5 kg, and the use of opiates was significantly reduced. Poor results were significantly related to preoperative use of tranquilizers and postoperative alcohol consumption. Neither patency of the anastomosis nor the time of observation were related to the operative result. The 8-year cumulative survival rate was 83 percent.

Adolescent↗
PubMed1987

Prediction of outcome of pancreaticogastrostomy for pain in chronic pancreatitis.

On the basis of 18 preoperative variables obtained consecutively in 31 patients undergoing drainage operation for pain in chronic pancreatitis, a preoperative discriminant score for satisfactory/unsatisfactory result is set up. The patient most likely to be free of pain after the operation has no preoperative use of tranquilizers, no diabetes, little dilatation of the pancreatic duct, no small pseudocysts, but daily use of opiates. This is probably not a matter of causal connection but rather an expression of common underlying pathophysiological mechanism(s), somatic or psychological. A pocket chart for the practical use in the preoperative assessment index is designed.

Adolescent↗
PubMed1986

Pancreatic tissue pressure and pain in chronic pancreatitis.

Pancreatic tissue pressure (PTP) was measured peroperatively by the needle technique in 14 patients with chronic pancreatitis undergoing drainage operations for pseudocysts (six patients) or dilated ducts (eight patients). All patients suffered from severe abdominal pain before the operation, and a pain evaluation was made at discharge and after 8-18 months of observation. PTP was increased in all patients and was not different in the two groups. PTP decreased significantly in both groups after drainage. Pain relief at discharge was good or fair in 12 patients and poor in one (one patient died postoperatively). During observation, pain returned in four patients. Long-term pain relief was not related to PTP decrease, PTP after operation, type of operation, or patency of anastomosis as seen by endoscopic retrograde pancreaticography.

Chronic Disease↗
PubMed1985

Indomethacin treatment of acute pancreatitis. A controlled double-blind trial.

Thirty patients with acute pancreatitis were allocated to indomethacin suppositories, 50 mg twice daily, or identical-looking placebo suppositories for 7 days in a controlled double-blind trial. The groups of patients were not different with regard to age, sex, etiology, or number of Ranson criteria. The number of days with pain and number of opiate injections were significantly less in patients treated with indomethacin. The median values of serum amylase and serum calcium were not different before or at any day during treatment. Bleeding from the gastrointestinal tract was not seen.

Acute Disease↗
PubMed1984

Pancreatic tissue pressure: techniques and pathophysiological aspects.

Pancreatic tissue pressure (PTP) was measured during surgery in six patients with a normal pancreas and in six patients with chronic pancreatitis. The pressures were obtained by insertion of a tiny transducer-connected cannula into pancreas. PTP probably reflects acinus and small-duct pressure. PTP was significantly higher in patients with chronic pancreatitis than in patients with a normal pancreas, but it decreased significantly after drainage. A high degree of linear relationship between PTP and intraductal pressure (r = 0.99) indicates that PTP measurements are valuable when the main duct is difficult to cannulate. Chronic pancreatitis might be a compartment syndrome due to impeded drainage and an inelastic capsule.

Aged↗