Biomedical subjects

N Eide

Publications and source records attributed to N Eide.

28 records · Page 2Linked to original sources

PubMed1989

Simultaneous bilateral primary choroidal melanoma.

The first published case from Norway of primary bilateral malignant melanoma of the choroid is presented. On the admission of a 73-year-old woman for a choroidal melanoma of the left eye, an asymptomatic tumour was detected in the periphery of her right eye. The left eye was enucleated. Histology confirmed the presence of a choroidal melanoma of the mixed type. After 3 1/2 years with regular follow-ups growth of the asymptomatic tumour was noticed. The fast growth was accompanied by a haemorrhage in the vitreous and a secondary retinal detachment. External radiation with a dose of 33.6 Gy resulted in a regression of the tumour, improvement of visual acuity to 0.5 and re-attachment of the retina, lasting the remaining 8 months of life. Multiple metastasis to the liver caused her death.

Aged↗

PubMed1989

Chronic ocular ischaemia.

Patients with carotid artery occlusive disease may develop ocular changes in both the anterior and posterior segments of the eye caused by chronic ischaemia. Four cases are reported with a wide variety of the characteristic ocular ischaemic symptoms and signs. Pulsed Doppler spectral analysis of the precerebral carotid arteries was used to detect the presence of relevant carotid occlusive disease. Diagnosis and therepy require an interdisciplinary approach, to prevent cerebral stroke and to preserve ocular function.

Aged↗

PubMed1987

Secondary retinal detachment interpreted as a part of uveal melanoma by CT-scan.

Four patients with histologically verified uveal melanomas were examined with computed tomography (CT) scan. Ophthalmoscopy revealed a sharply deliminated tumour surrounded by a secondary retinal detachment. The clinically calculated size of the tumours corresponded well with the histological specimens. The CT-scan indicated a greater size of the tumours. The discrepancies were due to difficulties in differentiation between the tumour tissue and the subretinal fluid which have almost identical CT-numbers. By combining axial and coronal views it was possible to distinguish the tumour from the secondary retinal detachment.

Adult↗

PubMed1987

Contusion rupture of the globe.

Severe contusion-injuries caused rupture of the globe in 20 eyes in 18 patients. 14 eyes had an open rupture (OR) and primary closure was performed in 13 eyes and one eye was enucleated. Six eyes with closed rupture (CR) had no emergency exploration. In both types of rupture, we intended to do vitrectomy within 14 days. In 12 cases vitrectomy was combined with retinal detachment surgery, lens extraction and gas injection. The upper-lateral quadrant close to the limbus was the most common site of rupture (12 eyes). In 8 eyes the length of the rupture exceeded one quadrant. The lens was extruded in 9 of 14 eyes with OR. Vision preoperatively was in all eyes only light perception. Useful vision (counting fingers or better) was obtained in 7 of 13 eyes with OR and 2 of 5 eyes with CR, excluding 2 totally blind eyes upon admission, one eye in each group. Three patients became totally blind, one patient was hit in her last eye and two patients had bilateral ruptures and these eyes could not be saved.

Adolescent↗

PubMed1987

A subhyaloid haemorrhage as the presenting symptom of bilateral optic neuropathy.

A 28 year-old man with a spontaneous vitreous haemorrhage as the first sign of Leber's optic atrophy is presented. The blood collected in a central retrohyaloid area covering the left macula. The exact starting point of the haemorrhage was never positively identified, but it seemed to originate from an area of microangiopathy adjacent to the optic disc. For 8-10 months the vision of the left eye gradually decreased to counting fingers. A year later the visual acuity dropped to the same level on the right eye. The picture was compatible with Leber's optic atrophy. Other disorders causing bilateral optic neuropathy were excluded. A careful family history revealed several cases of visual problems for several generations. Vitreous haemorrhage as the first sign of Leber's optic atrophy has not previously been reported. Peripapillar microangiopathy, however, has been described in the asymptomatic stage of the disease.

Adult↗

PubMed1986

Retinal break in an area with medullated nerve fibres.

Two cases of retinal breaks in areas with medullated nerve fibres are reported. The breaks were secured by argon laser treatment. A vitreous detachment may cause a slit-like tear by vitreoretinal traction in such areas.

Adult↗

PubMed1986

Visual evoked response in syphilitic optic atrophy. A case report.

A case of neurosyphilis is described. The presenting symptoms were reduced visual acuity and impaired colour vision. The examination revealed bilateral optic atrophy and acquired red-green colour defect. A syphilitic aetiology was based on positive serological tests in blood and CSF, pleocytosis and increased total protein in the CSF. The abrupt decline in visual acuity was arrested by treatment with penicillin and systemic steroids, but normalization of vision was not obtained. All VER-records, of P2 latencies and morphologies were surprisingly normal, but the amplitudes were reduced.

Color Vision Defects↗

PubMed1985

Pars plana lensectomy.

The results of pars plana lensectomy (PPL) in 36 eyes are reported. The average follow-up time was 9 months (2-24). The optical media became clear in all eyes. Post-operative visual acuity (VA) was greater than or equal to 0.6 in 31 eyes. Two eyes developed serious complications (retinal detachment in 1 eye and neovascular glaucoma in 1 eye). PPL represents minimal risks for the anterior segment, excludes problems with secondary cataract, presents optimal conditions for early contact lens fitting and for necessary treatment in the posterior segment. In the hands of an experienced surgeon PPL is effective and safe and offers an alternative treatment for patients up to the age of 30-35 years.

Adolescent↗

PubMed1984

Juxtapapillary chorioretinitis in neurosyphilis. A case report.

A case of neurosyphilis is described. The presenting symptoms were reduced vision and pain around the left eye. The examination revealed a juxtapapillary chorioretinitis and neurosyphilis with elevated total protein (0.84 g/l) and pleocytosis (250 cells X 10(6)/l) in the cerebrospinal fluid (CFS). Four months after treatment with penicillin for 10 days and prednisolone for 5 weeks, the ophthalmological signs had disappeared. There was no pleocytosis (4 cells X 10(6)/l), and the total protein content in CSF was almost normal (0.52 g/l). Treatment with 6 mill (IU) penicillin G intravenously every 6 h resulted in a concentration in serum and spinal fluid higher than the generally accepted treponemacidal level.

Adult↗

PubMed1983

Autosomal dominant partial lipodystrophy associated with Rieger anomaly, short stature, and insulinopenic diabetes.

We describe the clinical findings and natural history of an autosomal dominant form of partial lipodystrophy found in four affected individuals from three generations in the same family. The lipodystrophy was present from infancy/early childhood, involved primarily the face and local areas on the buttocks, and was nonprogressive. Affected individuals also had the Rieger anomaly, midface hypoplasia, short stature, retarded bone age, and hypotrichosis. An affected woman developed insulinopenic diabetes mellitus at 39 yr and another had glucose intolerance at 55 yr.

Adult↗