Biomedical subjects

N Eshaghi

Publications and source records attributed to N Eshaghi.

4 recordsLinked to original sources

PubMed1996

Laparotomy and proximal gastric vagotomy in Zollinger-Ellison syndrome: results of a 16-year prospective study.

OBJECTIVE: Pharmacological control of gastric acid hypersecretion in the Zollinger-Ellison syndrome has steadily improved, but medical treatment does not address the underlying tumor. The objective of this study was to evaluate the long-term effectiveness of a surgical approach to both tumor and acid hypersecretion in 22 patients with the Zollinger-Ellison syndrome. METHODS: Patients underwent laparotomy to resect tumors, combined with vagotomy to reduce acid secretion, followed by postoperative antisecretory therapy, if necessary. RESULTS: No surgical mortality or serious morbidity occurred. Tumor was found at laparotomy in nine patients (41%) and during long-term follow-up in an additional two patients (9%). Ten-year survival is 81%, with a long-term cure rate of at least 14%. Most patients (86%) have had long-term inhibition of acid secretion. Eight patients have discontinued regular use of acid-inhibiting medications. Patients requiring medication need less of it, and they have an improved acid inhibitory response to medication for up to 16 yr after surgery. CONCLUSION: Cure of the Zollinger-Ellison syndrome is possible in a minority of patients. Acid secretion can be safely reduced in almost all patients with laparotomy/vagotomy, usually allowing discontinuation, or reduced dose, of acid-inhibiting drugs. Long-term survival and quality of life are generally excellent.

Adolescent↗

PubMed1995

Thoracic splenosis: MR demonstration.

A previously diagnosed case of thoracic splenosis is presented along with recently acquired magnetic resonance (MR) images. The salient features of this interesting acquired condition are reviewed along with discussion of the MR findings and diagnostic implications of this rare complication of trauma.

Adult↗

PubMed1995

Fever of unknown origin following an upper gastrointestinal series in a patient with polycystic kidney disease.

Hematomas as a source of fever have been well recognized. We describe a patient with polycystic kidney disease (PCKD) who developed a fever of unknown origin following an upper gastrointestinal (UGI) series. Workup revealed a hemorrhagic cyst of a kidney at the level of the duodenum, where a paddle had been used during the upper GI series to compress the duodenum. Evaluation for the presence of infection, including blood and urine cultures, yielded negative results. This case indicates the importance of including hemorrhagic cysts in the differential diagnosis of fever in a patient with PCKD, particularly with a history of trauma. It is likely that fever develops due to the release of interleukin-1 by the hemorrhagic cyst.

Aged↗

PubMed1991

Plexiform neurofibroma of the pelvis: CT and MRI findings.

We present a case of plexiform neurofibroma of the pelvis in a patient with neurofibromatosis using magnetic resonance imaging (MRI) with computed tomography (CT) correlation. We discovered an extensive pelvic mass with a slightly greater signal intensity than muscle in T1-weighted images and a marked increased signal intensity in T2-weighted images. Multiple hypointense septations were identified throughout the tumor, particularly in the T2-weighted images. The MR appearance of pelvic plexiform neurofibroma is identical to those found in spinal and paraspinal locations. In the presence of an extensive pelvic mass in a patient with neurofibromatosis, MRI is recommended in evaluating and diagnosing plexiform neurofibroma. Since the MRI appearance of this tumor is characteristic, other lesions can possibly be ruled out. In addition, MRI's multiplanar capability is ideally suited to demonstrate the extension of these large tumors.

Adult↗