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Biomedical subjects

N F Abdrashitova

Publications and source records attributed to N F Abdrashitova.

10 recordsLinked to original sources
PubMed2002

[Peripheral blood morphology during chronic bronchitis complicated by the effect of ozone].

In workers afflicted with chronic bronchitis (ChB) after breathing ozone leukocytosis gives place to leukopenia against development of lympho-, monocyto- and neutropenia. In contrast to the workers, in citizens who have not previously contacted ozone chronic obstructive bronchitis is characterized by leukocytosis with less expressed lympho- and neutropenia. Changes in peripheral blood in ChB patients (development of leuko-, lympho-, monocyto- and neutropenia) grow drastically in 5-8 years of ozone inhalation.

Adult↗
PubMed2001

Effects of antibiotics on reactive oxygen species generation by neutrophils.

Antibiotic therapy of patients with exacerbation of chronic obstructive bronchitis exposed and not exposed to ozone did not improve oxidative metabolism in neutrophils. Cefazolin, ceftizoxime, and gentamicin normalized functional biocidal reserves of neutrophils, which correlated with pronounced therapeutic effects.

Ampicillin↗
PubMed2001

[On some basic issues and factorial structure of ecological pulmonology].

Consideration is given to the place occupied by diseases of respiratory organs in the general structure of morbidity. In many ways, growth in their number has been determined by amplification of anthropogenic factors. This is manifested in emergence of new eco-dependent diseases and syndromes including more difficult course of pulmonary pathology. One of the prioritized disciplines of the modern pulmonology is ecological pulmonology which lies in the domain of medical ecology and is central to the concept of eco-dependent human diseases. A factorial structure of ecological pulmonology built on the etiological principle is proposed to facilitate inquiry into the origin and course of various forms of eco-dependent pathology of the lung.

Adolescent↗
PubMed2000

Effect of long-term exposure to ozone on functional activity of human phagocytes.

Functional activity (biocidal properties) of whole blood phagocytes from humans exposed to ozone was studied by measuring spontaneous and zymosan-induced luminol-dependent chemiluminescence. Generation of reactive oxygen species and biocidal properties of phagocytes depended on the time of ozone exposure and development of bronchopulmonary diseases. The data suggest that generation of reactive oxygen species must be assayed for elaboration of individual patient management programs.

Adult↗
PubMed2000

[Comparative study of ion homeostasis and lipid peroxidation in human serum during prolonged exposure to ozone].

Concentrations of the ions of calcium, sodium, potassium, chloride-anions and end-products of lipid peroxidation in blood serum of patients with bronchopulmonary pathologies were investigated on a background of prolonged exposure in ozone. Ion homeostasis was found to alter as products of lipid peroxidation accumulated. Suppositions regarding possible mechanisms of impairment of ion homeostasis were made.

Adult↗