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Biomedical subjects

N F Deĭneko

Publications and source records attributed to N F Deĭneko.

12 recordsLinked to original sources

[The characteristics of the dispensary observation and treatment of patients with duodenal peptic ulcer following organ-preserving operations].

An analysis of results of organ saving operations in combination with selective proximal vagotomy in 234 patients with duodenal ulcer revealed that one of the causes of unfavourable treatment outcomes is the development of erosive-ulcerative lesions of the stomach. The leading etiological factors for distal gastritis in duodenogastric reflux, for proximal gastritis-ischemia of the gastric wall in the devascularization zone. Individualized treatment with consideration of the etiopathogenesis of postoperative gastritis allows to reduce the frequency of development of postvagotomy disorders by 19.8%.

Aftercare↗

[Erosive gastritis after an organ-preserving operation for duodenal ulcer].

Examined were 243 patients with duodenal ulcer after the operation of selective proximal vagotomy. Pyloroplasty was performed in 49.9%, duodenoplasty in 53.1%. A 1-2 year follow-up revealed erosive gastritis in the proximal region in 18.5%, in the antrum in 13.9%, combined location in 5.8%. Differences in the mechanisms of formation of erosions in different zones of the stomach in erosive gastritis were established. The tactics of treatment of erosive gastritis is discussed.

Adult↗

[Plasma fibronectin level in patients with chronic diseases of the liver].

The diagnostic value of determination of plasma fibronectin in chronic hepatic diseases was examined on the basis of the data available in the literature and the authors' own results of studies. The procedure for measuring fibronectin in healthy subjects and patients with hepatic cirrhoses and chronic persistent hepatitis is briefly outlined. Possible mechanisms of fibronectin level alterations are discussed in these pathological processes.

Adolescent↗

[Blood levels of pituitary gonadotropins, sex hormones, gastrin and cAMP in duodenal ulcer].

Radioimmunoassay was employed to measure blood levels of LH, FSH, testosterone, estradiol, progesterone, estriol, gastrin and cAMP in 184 duodenal ulcer patients (141 males and 43 females) and 81 controls (40 males and 41 females). For duodenal ulcer patients hypophyseal gonadotropic function was activated while the blood picture of sex hormones is sex-related. Functional balance between the study hormones typical for healthy subjects in duodenal ulcer was found impaired. Derangement of hormonal homeostasis of hypophyseal-gonadal system of the blood and its functional relations with gastroduodenal system may be a contributing factor in pathogenesis of peptic ulcer.

Adult↗