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Biomedical subjects

N F Driuk

Publications and source records attributed to N F Driuk.

At least 19 recordsLinked to original sources

[Method of surgical treatment of "elephantiasis" of the limb: old philosophy, new approach].

The authors had summarized more than 25-year experience of surgical treatment of patients with the lower and upper extremities lymphedema. The aspiration-resectional-plastic method of treatment of severe forms of the limb lymphedema, which intends in the first stage the resection of fibrously changed tissues, preserving the portion of slightly changed cutaneous-subcutaneous flaps and regions in projection of localization of main lymphatic collectors, under which aspiration lipectomy is performed. Postresectional wound surface is covered with special synthetic tissue. In the next stage, after appearance of granulation tissue, autodermoplasty is performed. Two-staged cutaneous plasty and repeated aspirational lipectomy provides for optimal survival of full thickness cutaneous transplants, reduction of the limb volume, improvement of the lymphatic system draining function.

Adult↗

[Surgical tactic in the injury of neck vessels].

Retrospective analysis of the surgical treatment results in 50 injured persons with the damage of the neck vessels in 1998-2003 yrs period was presented. Restorational-reconstructive operations were performed in 19 (38%) injured persons with the arteries damage, in 10 (20%)--with the veins damage, the ligature operations were done, accordingly, in 6 (12%) and in 20 (40%). Satisfactory result was noted in 41 (82%) injured persons. Neurological complications had occurred in 4 (8%) of patients. Mortality had constituted 10% (5 patients died). The principles of surgical treatment of the neck vessels damage were stated.

Adolescent↗

[Surgical treatment of injured persons with the main blood vessels damage].

Retrospective analysis of the surgical treatment results of 45 injured persons with damage of main blood vessels was presented. Specific operative methods in injury of the different type main blood vessels, localized in thoracic and abdominal cavities, were depicted. In 35 (77.8%) injured persons good and fair results of restoration operations were noted. The lethality rate was 22.2%. The tactic of surgical treatment of the main blood vessels injury was presented.

Adolescent↗

[Current possibilities of the diagnosis and surgical treatment of acute thrombophlebitis and severe forms of varicose disease].

The data on examination and surgical treatment of 35 patients, suffering severe forms of varicose disease in stage of trophic disorders occurrence and with an acute thrombophlebitis are adduced. The concept of an active surgical help, including thromboembolic complications prophylaxis, depending on thrombophlebitis localization, correction of the venous hemodynamics disorders and the staged closure of trophic ulcer is substantiated. Introduction of the proposed tactics had permitted to achieve satisfactory outcomes, including the trophic ulcer healing and the trophic disorders regression in all the patients operated on.

Acute Disease↗

[Prophylactic and correctional measures for thromboembolic complications in performance of the upper extremity replantation and microvascular autotransplantation of combined complex of tissues].

There were analyzed the causes and factors, influencing the thromboembolic complications frequency, in performance of the upper extremity segment replantation in 220 injured persons and of microsurgical the tissues defect plasty using combined complex of tissues (CCT)--in 154 patients. The role of anticoagulational therapy in complex of remedial measures, directed on the occurrence prophylaxis and medicinal correction of hemodynamic disorders in microvascular anastomoses after the operation, was determined. The advantages of low-molecular weight heparin (Fraxiparine) administration in comparison with the standard heparinotherapy were showed: lowering of thromboembolic and hemorrhagic complications occurrence frequency, the unique method of Fraxiparine subcutaneous injection into the replanted segment and CCT was presented.

Adolescent↗

[Compression syndromes in chronic venous insufficiency of lower extremities].

Results of examination and surgical treatment of 77 patients with severe forms of chronic venous and lymphovenous insufficiency of lower extremities were analyzed. The compression syndrome concept and its role in pathogenesis of severe forms of chronic venous and lymphovenous insufficiency of lower extremities were determined. There was elaborated the tactics of complex treatment of patients, application of which had permitted to achieve the trophic ulcers healing in 98% operated patients, previously considered noncurable.

Chronic Disease↗

[Experimental studying of the possible pharmacological defense of muscular flap tissues from ischemic and reperfusion injury during its free transplantation].

In experiment on muscle flaps of 20 rabbits the peculiarities of their tissues damage in the ischemia period, and also due to the oxygen-dependent processes activation (peroxidal and free radical oxidation of a membrane phospholipids) in period of its reperfusion were studied. Preliminary introduction of a lipin, unitiol and ascorbic acid mixture in the flap arterial channel had promoted the reduction of damage severity in the translocated flap cells biomembranes due to ischemia and reperfusion, causing inhibition of the lipids peroxidal oxidation processes, rising of the flap tissues antioxidant defense, the cell and subcell membranes stabilization which preserves the vessels endothelium integrity. This showed a promising future for application of these preparations in a free transplantation of compound tissue complexes.

Animals↗

[Experimental substantiation of a two-staged method of microsurgical transplantation of the complex composite flaps].

The authors have proposed two-staged flap transplantation, consisting of flap mobilization on vascular pedicle with subsequent its transplantation in several days. In experiment on muscular flaps, obtained from regio epigastrica of 30 rabbits, it was established that optimal time for the second stage of operation conduction may be end of the second--beginning of the third day after the transplant mobilization.

Animals↗

[Restorative microsurgery in severe injury and traumatic amputation of the distal portions of the extremities].

Application of microsurgical methods and free grafting of the compound complexes of tissues with the vessels and nerves in particular with microanastomoses permitted to achieve high functional results in traumatic amputation of extremities in contiguity, severe destroying traumas and their consequences. Experience of 1000 urgent microsurgical operations, including 638 replantations of digits and their blocks for various kinds of amputation on the palm level was summarized. Classification of amputation, taking into account the injury mechanism and character, promoting the choice of optimal tactic and technique of restoration operation was elaborated. Indication for replantation are substantiated, the results of restoration operation, complications occurring after large segments of extremities replantation and measures for their treatment are analysed. Definite success of operation is determined by the extent of first operation and by subsequent rehabilitation measures conduction including the correcting operations and various conservative methods.

Amputation, Traumatic↗

[The development and introduction of diagnostic and treatment methods for neurovascular diseases of the upper extremity].

The diagnosis complex, permitting to reveal the disease cause and the character of the affect faulty and quickly, was elaborated, based on the experience of treatment analysis of more than 600 patients with the upper extremities neurovascular diseases--thoracic inlet syndrome, Raynaud disease and syndrome. Methods of conservative therapy are introduced, indications for operative treatment are substantiated. Application of new methods of restoration-reconstructive interventions permitted to raise the treatment quality, particularly in seriously ill patients with complicated forms of upper extremities neurovascular diseases.

Arm↗

[Revascularization in the skin loss with skull fornix bone exposure].

Experience of 69 patients treatment, suffering the soft tissues death with uncovering or partial necrosis of the skull vault bones, occurring after burns and mechanical injuries was summarized. Multiple milling (4 patients) of the uncovered bones is dangerous, lacks efficacy, leads to osteomyelitis and the skull vault defects development. The skull bones revascularization with cutaneo-subcutaneous, complex-composite flaps bringing nutrition from outside was proposed and accomplished. Revascularization methods are depicted, their results are presented in 65 patients. The revascularization conduction in term to 40 days after the injury occurrence permits to reduce the time of treatment, to avert the skull vault bones necroses, to gain good functional results.

Adolescent↗

[Use of vazaprostan in the treatment of multifocal peripheral obliterating lesions of arteries of the lower limbs].

Vazaprostan was prescribed to 13 patients with the lower limbs obliterating atherosclerosis and the coronary arteries atherosclerotic lesion (first group) and in 17--with obliterating atherosclerosis and endarteritis of the lower limbs vessels (second group). The treatment was found to be effective one in all of the patients of the first group and in 13--of the second. The authors consider vazaprostan application to be expedient in patients with the lower limbs obliterating lesions as a supplement to operative intervention and also in coincidence of this pathology with the ischemic heart disease.

Aged↗

[Surgical treatment of multistage occlusion of the abdominal aorta and iliac and femoral arteries].

The results of surgical treatment of 26 patients with "multistage" occlusion, who underwent reconstructive operation on two segments (group 1), and 29 patients, who underwent ultrasound disobliteration of the femoral arteries together with the reconstructive operation (group 2), are presented. In group 1, a good immediate result was noted in 80.8%, a good long-term result--in 61.6%, in group 2--79.4 and 70.8% of the patients, respectively.

Adult↗

[Comparative evaluation of the methods for treatment of compressive thoracic outlet syndrome].

The co-operative investigation of two clinics on the basis of examination and treatment of 78 patients with the thoracic outlet syndrome for 5 years is presented. The comparative assessment of the two main methods for surgical treatment--1st rib resection and resection of the anterior scalene muscle has been performed. The results of less traumatic operation of the anterior scalene muscle resection employed in certain forms of the disease are similar to those in performance of more radical operation, the incidence of complications is lower.

Adolescent↗

[Lymphatic vessel and venous anastomosis in the treatment of patients with lymphedema].

Examination and surgical treatment of 31 patient with primary (17 cases) and secondary (14) lymphedema of an extremity at a stage of fibredema was carried out. It was established that a degree of increase in the volume of an extremity rather often didn't correspond to a stage of fibredema, pathological changes in the lymphatic vessels were pronounced to a different degree. However, this do not exclude possibility of their effective use for placing lymphoangiovenous anastomosis.

Adult↗

[The application of lymphovenous anastomoses in the treatment of primary lymphedema of the lower extremities at the edema stage].

The experience with clinical observation and surgical treatment of 217 patients with primary lymphedema of the lower extremities at stage II, IIIA (stage of "dropsy") is summarized. The working classification and developed complex of the diagnostic methods used are presented. The indications for the operations of creation of the lymphoangiovenous, lymphonodulovenous anastomoses, and as well the use of combined operations are considered; their effectiveness in different types of lesions of the lymphatic vessels is assessed. The methods for prevention of the erysipelatous inflammation recurrence with the use of endolymphatic intranodular administration of antibiotics are suggested. A complex of the developed measures permitted to obtain a satisfactory result at the nearest postoperative period in 74% of the patients, at the period of from 4 to 7 years--in 57%.

Adolescent↗