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N G Gladkovich

Publications and source records attributed to N G Gladkovich.

14 recordsLinked to original sources
PubMed1991

[The morphometric characteristics of the neurons of the reticular nuclei in the brain stem in the kitten].

In the brain stem of 30-day-old kittens three types of Golgi-stained neurons are distinguished: sparsely branched reticular neurons, densely branched arborescent neurons and multipolar giant neurons (according to the classification by Leontovich). Implication of the new method of computer morphometry permits obtaining formalized characteristics of 23 parameters of the above types of neurons. An analysis of the quantitative characteristics of the studied neurons has revealed statistically significant differences in most parameters. This fact permits advancing a conclusion about morphological identity (stability) of each type of the neurons. Structural differences and similarities in reticular nuclei are discussed with respect to their functional features.

Animals↗
PubMed1991

[The effect of sectioning the lingual nerve on the morphometric characteristics of the reticular nuclei in the brain stem in the kitten].

Three subpopulations of Golgi-stained neurons of the brainstem reticular nuclei have been studied by the method of computer morphometry in 30-day old kittens. 23 parameter of the neuronal geometry were analyzed after uni-and bilateral lingual nerve section 5-7 days after birth. All of cells display statistically valid changes in some parameters, typically differing in every group: for reticular neurons--free distribution of dendrite endings in the dendritic field; for arborescent ones--the length of dendritic segments; for giant multipolar neurons--distribution of foci of maximal dendrite branching in the dendritic field. Unilateral lingual nerve section gives more pronounced quantitative deviations from the normal state, than bilateral one.

Animals↗
PubMed1991

[Dendrite orientation in neurons of the reticular brain stem nuclei of a kitten after oral deafferentation].

Deviations in orientation of dendrites in neurons of the reticular brainstem nuclei are demonstrated in the Golgi preparations of the brain of 30-day old kittens by means of the computerized morphometry. Changes in the density of dendrite orientation occurring after bilateral and unilateral lingual nerve section are considered with respect to the following afferent inputs: midline structures and trigeminal and vestibular nuclei.

Afferent Pathways↗
PubMed1985

[Quantitative morphologic characteristics of neurons of the sensory nuclei of the trigeminal nerve developing after partial deafferentation].

Five types of neurons were studied in the sensory nuclei of the trigeminal nerve stained by the Golgi method in kittens aged 30 days with bilateral transection of the lingual branches of trigeminal nerve made on the fifth postnatal day. Partial deafferentation resulted in changes of dendrite apparatus of reticular, arborescent and bushy neurons (68.61 and 48% of neurons changed). Short-dendritic cells changed slightly. The multipolar giant neurons underwent practically no changes. All the changes could be divided into two groups: destructive changes and constructive changes. The destructive changes consisted in the decrease of cell body sizes, number, length and ramification of dendrites and constructive changes--in the increase of these parameters. Various types of trigeminal neurons responded to deafferentiation in different ways. Bushy neurons displayed mainly destructive changes and reticular and arborescent neurons--both destructive and constructive ones.

Animals↗
PubMed1982

[Correlations of the geometric and electrophysiologic characteristics of brain stem neurons in the kitten].

Spike activity of the medially and laterally localized units was compared in the pontomedullar reticular nuclei on 1-5 and 15-30 day old kittens. The amplitudes of spikes, spontaneous and evoked patterns of firing in the lateral and medial groups were different. The ratio of cells responding to single and high-frequency stimuli was lower in the lateral units and higher in the medial ones. The medial units had a more significant background firing activation in the interstimulus intervals. It is supposed that the medial cells reflect the properties of densely ramified giant neurons and the lateral--those of the sparsely ramified units. The difference between their electrophysiological properties may be connected with the dendrite geometry, especially with maximal branching foci of dendrites.

Action Potentials↗
PubMed1982

[Quantitative morphologic characteristics of developing neurons of the sensory nuclei of the trigeminal nerve in the kitten].

The paper presents a quantitative Golgi study of the kitten sensory trigeminal complex. Kittens of 1-5 and 30 days were used. Trigeminal neurons were divided into five groups. Neurons of two groups ramified sparsely and were defined as "reticular" and "short dendritic" neurons. Neurons of three other groups ramified densely and were defined as "bushy" neurons, "arbory dendritic" and "multipolar giant" neurons. The quantitative morphological data were obtained by measuring cell sizes, number, length, relative length, degree of branching of dendrites and total cell branching. The neurons of different groups had different parameters and a special mode of their maturation. "Bushy" neurons showed regressive changes during ontogenesis. All their parameters were reduced during the first month. Foci of maximal dendritic branching were displaced towards the distal portions of dendrites during the processes of cell maturation. All trigeminal neurons reached the high degree of maturity at birth.

Animals↗
PubMed1980

[Quantitative morphologic characteristics of developing brain stem reticular formation neurons].

The paper presented results of a quantitative Golgi study of developing neurons of the brain stem reticular nuclei of prenatal and newborn kittens. Age of prenatal animals was 45-55 days, that of newborns 1-5 and 30 days. The neurons were divided into sparsely ramified reticular and densely ramified multipolar giant ones. The quantitative morphological data were obtained by measuring cellular sizes, number, length and degree of branching of dendrites and general cell branching. The neurons of both kinds had different parameters and special features of their maturation. A higher degree of branching was observed in the fetus. Foci of maximal dendrite branching were localized in proximal and distal portions of dendrites in the fetus and 30-day old kittens, and only in proximal portions in the infant kitten. An attempt was made to correlate morphological and electrophysiological properties of the neurons under study.

Animals↗
PubMedDate not supplied

[The quantitative morphological characteristics of the neurons of the anterior horns of the spinal cord in the kitten].

Golgi preparations of cervical part of the spinal cord of 30-day kittens were used to study sparely and densely branching neurons of lamina VII, sparely and densely branching neurons of lamina VIII and big densely branching motor neurons (as classified by Leontovich) of medial and lateral regions of lamina IX. Qualitative morphological characteristics of geometry of each cell type were obtained by the method of computerized morphometry. The details of the structure of neurons belonging to different laminae of grey matter are discussed.

Animals↗
PubMedDate not supplied

[The quantitative morphological characteristics of the spinal neurons in the kitten developing under conditions of limited afferent input].

Golgi preparations of cervical part of the spinal cord were used to study sparely and densely branching neurons of lamina VII, sparely and densely branching neurons of lamina VIII and large densely branching motor neurons of lamina IX in 30-day kittens developing under the conditions of limited reticulospinal input. Limitation was induced by electrocoagulation of bulbar magnocellular nucleus and caudal reticular pontine nucleus performed at the 7th day. Computerized morphometry revealed that partial deafferentation affects the geometry in all studied cell types except densely branching neurons of lamina VIII. Adaptive nature of structural reorganization of spinal neurons and possible relationship between morphological properties and functional profile of cells are discussed.

Animals↗
PubMedDate not supplied

[Organization of early forms of kitten behavior after partial oral deprivation].

Study of development of early forms of behaviour was carried out on intact kittens of the first month of life, who endured in 5 days age uni- and bilateral sections of the lingual nerve, and on shame-operated and undernourished animals. It was shown that bilateral deafferentation caused significant disturbance of alimentary behaviour at the stage of sucking, manifested in disturbance of natural sucking and appearance of shame sucking, i.e. rhythmic sucking movement without nipple grasping. At the one-month age, in conditions of artificial feeding, natural sucking in operated animals was restored and the shame one disappeared. Bilateral section of the lingual nerve led to acceleration of ripening of sensory and motor systems and accelerated development of homing, exploratory and playing behaviour. Possible role is discussed of sensory trigeminal nuclei neurones in organization of normal patterned sucking and at limited sensory inflow. It is suggested that elimination of sensory input developing in the norm earlier than others, changes natural terms of other channels development, what accelerates the change of early behaviour forms.

Aging↗