PubMed Health⌕ Search

Biomedical subjects

N G Graham

Publications and source records attributed to N G Graham.

18 recordsLinked to original sources
PubMed1989

Self-governing hospitals: a hospital manager's assessment.

The development of the resource management initiative on the basis of credible accurate information systems would lead to a change from the existing arbitrary resource allocation method of hospital funding to true budget determination on a direct line management basis. Contracts for hospital services would be irrelevant and the professional relationships between doctors and patients would be retained.

Budgets↗
PubMed1976

Alpha-globulins in the surveillance of colorectal cancer.

The alpha1 and alpha2-globulins have been studied at various stages in the evolution of colo-rectal cancer. The alph2 was elevated in some primary tumours and rose in metastatic cancer especially when it involved the liver. Some apparently tumour free patients had an unexplained elevation of alph2-globulins. The macroglobulins were not a major constituent of the raised alpha2-globulins. Haptoglobulin levels were found to be a useful indicator of tumour activity, when their level was raised in metastatic cancer it was usually with an antecedent or coincidental rise of plasma CEA. Primary tumours may cause a high haptoglobin response without an elevation of CEA.

Alpha-Globulins↗
PubMed1975

Acute pancreatitis.

A general survey of acute pancreatitis has been given, with the emphasis on diagnosis and management. Attention is drawn to the difficulties that sometimes arise in the accurate diagnosis of the acute upper abdominal illness and in the assessment of complications arising during the treatment of acute pancreatitis. The importance of the routine use of 'Trasylol' (aprotinin) during the acute attack is emphasized. The indications for operation are discussed in relation to achieving accurate early diagnosis, the management of certain complications and the prevention of further attacks. The mortality rate of acute pancreatitis has dropped considerably with improvement in the diagnostic rate and the routine use of intensive conservative treatment, but the prognosis of septic complications is still grave and will be improved only by the universal recognition that pancreatic suppuration is no ordinary septic process and that the timing of surgical drainage is critical.

Acute Disease↗
PubMed1971

Reliability of physical signs in patients with severe attacks of ulcerative colitis.

A series of observer variation studies in a small group of patients suffering from severe acute ulcerative colitis is reported. Seventy-two separate assessments of the patients' physical signs and clinical progress were made by three independent observers.The results of this investigation suggest that there is difficulty in eliciting general physical signs such as anaemia or dehydration in these patients. By contrast, local abdominal signs such as tenderness and distension were relatively reliably elicited. The results also suggest that there are considerable problems in evaluating these clinical signs in terms of the patient's immediate subsequent progress.

Acute Disease↗