[Skin syndrome of drug disease].
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Biomedical subjects
Publications and source records attributed to N G Kochergin.
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A case of a three-month carrier-state of P. aeruginosa in the hands' skin of a nurse in a newborns reanimation department is described. The carrier state did not seize after the nurse was isolated from work and was related with colonization of the dermal tissue, therefore, it could be detected only after the hands' skin was treated with a detergent solution. The carrier state was arrested after a chemotherapy course with cyprofloxacyn administered both locally and perorally.
Alimentary allergy has been studied in 16 patients with atopic dermatitis and in 4 ones with common psoriasis (a reference group) by measuring the concentrations of specific and total immunoglobulin E with the 3M IgE fluoroallergosorbent test. The method has proved to be highly sensitive for the detection of IgE-dependent alimentary allergy contributing much to the pathogenesis of atopic dermatitis.
The traditional oral examination in clinical dermatology is not devoid of shortcomings, the principal of which are subjective estimation of the students' knowledge and a random control. A written examination, representing a complex of tests, is devoid of these drawbacks. The authors share their two-year experience with such examinations, combined with the control of mastering the practical skills in dermatology and venereology. The major advantages of a written test-based examination in a clinical discipline are an objective estimation of the students' knowledge, a universal complex of tests equally difficult for all the students, permitting the control of knowledge in practically all sections of the curriculum, and a more rational organization of the examination session. Such examinations are recommended for dermatology and venereology chairs.
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Using the complex of methods for recognition of surface lymphocyte receptors the authors examined 42 patients with chronic lymphatic leukemia and 30 healthy individuals. The reduced density of receptors on lymphocyte surface or their total absence is characteristic of the whole group of patients with chronic lymphatic leukemia. This atypism of leukemia lymphocytes is augmented in greater rate of neoplastic cells growth. Total synthesis of serum immunoglobulins in chronic lymphatic leukemia is found to be lowered, the fall being more sharp in increased amount of lymphocytes in peripheral blood.
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