N G Li | PubMed Health

PubMed1989

[Interhemispheric subdural empyema].

Six cases of interhemispheric subdural empyema are reported. It is a rare disease due to different infections origins. All of them are under 24 years old. The characteristics symptoms of these cases were intracranial infection, increased ICP, cerebral falx syndrome and focal seizure. The specific appearances on the films of angiography and CT scan were discussed. It could be located these lesions exactly. The surgical treatments were continuous drainage though cranial burr hole or excision of abscess. All 6 cases are cured with no recurrence.

Adolescent↗

PubMedDate not supplied

[Various causes of decreased aldehyde dehydrogenase activity in the rat liver and blood in chronic alcoholic intoxication].

Dynamics of accumulation of alcohol- and aldehyde dehydrogenases inhibitors in liver tissue of rats with chronic alcohol intoxication showed that content of the bioinhibitors of protein nature was increased during the animals alcoholization, whereas inhibition of aldehyde dehydrogenase was more distinct as compared with alcohol dehydrogenase. When the nature of aldehyde dehydrogenase inhibitor was studied using the immunoenzyme analysis, the inhibitor proved to be an autoantibody, produced in chronic alcoholization of rats as a result apparently of the enzyme modification. Titre of specific antibodies to "autoantigen" (aldehyde dehydrogenase from liver tissue of alcohol consuming rats) was 12-16-fold higher in liver tissue and blood serum of rats with alcoholism as compared with the corresponding preparations of control animals. An immuno-enzymological mechanism, responsible for an increase of acetaldehyde content in blood developed after ethanol consumption in alcoholism, is discussed.

Acetaldehyde↗