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Biomedical subjects

N G Proença

Publications and source records attributed to N G Proença.

34 records · Page 2Linked to original sources
PubMed1977

[Immunopathological studies in herpes gestationis].

Immunologic studies were made in two patients with "herpes gestationis". Direct and indirect immunofluorescence studies lead to the following results: 1. DIF was done with antisera against IgG, IgM, IgA, IgE and C3. Only the deposit of C3 was detected on the basal membrane zone of the lesioned skin. In one of the patients the deposit was found also on healthy skin. 2. IIF did not show immunoglobulins against the basal membrane in sera but in both patients a termolabil factor (factor HG) which activates the fixation of the complement onto the basal membrane zone was detected. No correlation between the immunopathologic pattern of Herpes gestationis and that of the other bullous diseases which cause subepidermic bullae was found. However there was a significant similarity between the immunologic pattern of Herpes gestationis and Bullous pemphigoid.

Adult↗
PubMed1977

[Multiple eccrine spiradenomas. Apropos of 2 cases in 2 sisters].

Two cases of multiple eccrine spiradenoma were studied, representing respectively up to the present time the 7th and 8th registered cases in the world literature. These cases two are siblings, a fact that had never been observed before. The histogenesis of the tumour has been the subject of controversy. The presence of multiple lesions in each patient and the incidence in siblings are two important points in favour of the naevic character of eccrine spiradenoma. Among other therapeutic measures we wish to draw attention to the excellent result we obtained with small doses of radiotherapy (1,500 rads divided in ten applications). It should be kept in mind that remission of the disease may only be temporary.

Adenoma↗
PubMed1976

[Aspects of cutaneous sarcoidosis in Brazil].

This study collects all cases of sarcoidosis with cutaneous involvement referred to in the Brazilian literature. Only 40 cases could be found confirming the rarity of the disease in Brazil. With regard to these cases the following aspects of the disease were studied: age, incidence, race and sex distribution, origin of patients, clinical forms, systemic involvement, behaviour of the intradermic reactions and histopathology. Some characteristics could be established: 1) Females are most frequently affected than males. 2) No racial differences were noticed as far as the caucasian and the negroid are concerned. 3) The onset of the disease occurred between 16 and 69 years of age (mean age 37). 4) All patients originated from the south-central region of the country. 5) The most frequent cutaneous forms were associations of papulous lesions, nodular lesion and plaques. 6) Besides the skin, involvement of lymph nodes, bones, liver, eyes, spleen, salivary glands, heart, bowels and the facial nerve could be found. Heerfordt syndrome (uneoparotidic fever) was seen only once. Death occurred twice. 7) Kveim test was positive in all 11 cases in which it was done. Tuberculin and lepromin tests resulted in weak reaction or its complete absence. 8) All cases were confirmed by histopathology. Eight of the forty biopsies were reexamined by the authors themselves.

Adolescent↗
PubMedDate not supplied

[Dermatophytosis in childhood: clinical and therapeutic aspects].

Dermatophytoses have peculiar aspects in children, making them different from adult dermatophytoses. The author reviewed 139 of his personal cases to evidence these peculiarities; based on these cases he was able to discuss: a) clinical aspects of dermatophytoses and the frequency of each form in the child; b) analysis of the species of dermatophytes isolated in the 101 patients studied. The author adds a therapeutical orientation for cases of dermatophytosis in children.

Arthrodermataceae↗
PubMedDate not supplied

[Thalidomide: an eclectic medication in dermatology].

The authors review the indications for the use of thalidomide in dermatological conditions. They consider leprotic reaction, prurigo nodularis of Hyde, actinic prurigo, discoid lupus erythematosus, Weber-Christian panniculitis, recurrent mouth aphtosis, Behcet's syndrome, and pyoderma gangrenosum. The dramatic situation created by the use of thalidomide in the sixties not-withstanding, interest in its use is warranted within certain limits due to its wide therapeutic action.

Humans↗