[Reorganization of the neuromediatory function of the brain and autonomic regulation at rest during adaptation to chronic hypokinesia].
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Biomedical subjects
Publications and source records attributed to N G Zhuravleva.
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The study shows that chronic hypokinesia (7-8 months) in rats, analogous to that in humans, causes constant reduction in activation level and results in the development of rearrangements in brain slow bioelectric activity. The rearrangements initiate decrease of the general level of brain activity and compensatory rise of its response to environmental signals. A likely mechanism of the rearrangements of the first type can be characterized by amplification of recurrent stopping processes and that of the second type by raising efficacy of the synaptic system functioning.
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The integral activity of main frequency ranges of the rest EEG was studied in two groups of schoolchildren at the end of the schoolyear. One half of each group consisted of boys, the other one of girls. The groups differed in the number of physical culture lessons per week (2 and 8). The boys of the two-lessons group manifested a higher integral oscillation activity over the whole EEG spectrum as compared with the boys of the eight-lessons group; this was considered as a drop of activation level. At the same time the girls of the two-lessons group revealed a higher integral activity within the theta range and a lower one within other ranges; this was estimated as an EEG manifestation of traces of tense alertness. Judging by the result of dispersion analysis, the influence of chronic hypokinesia on the recorded EEG components is much greater than that of the school activities.
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Light flashes, indifferent to the subject, of 5 msec duration and of 0.27 joule intensity, were presented during school period to two groups of children with different levels of motor activity. The school children whose mobility was by 40 to 45% below the physiological norm exhibited longer latencies of late P3 and O3 components of averaged visual evoked potentials. It is assumed that the longer latencies are due to a lowered level of functional activity of the non-specific brain structures working in conditions of hypokinesia in a more synchronized regime. The introduction of a daily lesson of physical exercises of enhanced motor activity suffices to compensate for disturbances in the brain integrative activity, caused by hypokinesia.