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Biomedical subjects

N Galanis

Publications and source records attributed to N Galanis.

15 recordsLinked to original sources
PubMed2006

Forced expiratory volume in one second and peak expiratory flow rate values in non-professional male tennis players.

AIM: Forced expiratory volume in 1 second (FEV1) is a reliable and easily measured lung function index, which is nowadays used for early detection of chronic obstructive pulmonary disease. It has also been established recently as an important predictor of all-cause, cardiovascular and cerebrovascular morbidity and mortality in the Western World. Similar implications have been made with regard to peak expiratory flow rate (PEFR). The present study was designed in order to compare the FEV1 and PEFR values of non-professional, smoking and non-smoking male athletes to those predicted for the general, non-athlete population. METHODS: A total of 141 non-professional tennis players aged 30-74 years were studied (99 smokers and 42 non-smokers). FEV1 and PEFR of all men were measured by means of a one flow spirometer, and compared to those predicted for their age and height, based on formulas for the non-athlete, healthy, non-smoking population. RESULTS: Non-professional tennis players had significantly higher FEV1 and PEFR values, compared to FEV1 and PEFR predicted, respectively. No statistically significant difference was observed between smokers and non-smokers. CONCLUSIONS: Our study confirms that even moderate physical activity, such as non-professional tennis, can improve FEV1 and PEFR values, maintaining a normal respiratory function, which is a strong predictor of reduced cardiovascular and overall morbidity and mortality. FEV1 and PEFR are easy to measure parameters that should be used more often for the assessment of general health status.

Adult↗
PubMed1999

Surgical management of short bowel syndrome by construction of an isoperistaltic intestinal valve: an experimental study in dogs.

OBJECTIVE: To develop of an isoperistaltic invaginated valve for the treatment of short bowel syndrome. DESIGN: Randomised experimental study SETTING: University Hospital, Greece MATERIAL: 8 mongrel dogs INTERVENTION: 90% resection of the small bowel, followed by construction of an invaginated valve one month later. MAIN OUTCOME MEASURES: weight loss, fat excretion in the faeces, radiographic and histological examination of the valve, pressure curve along the valve. RESULTS: Weight loss and steatorrhoea were reversed over a period of 2-3 months without evidence of intestinal obstruction in any of the animals. CONCLUSIONS: The construction of an isoperistaltic invaginated valve could be a solution to the management of the short gut syndrome.

Animals↗
PubMed1988

Local transposition flap for valve construction in short-gut syndrome.

In 10 mongrel dogs, massive resection of small intestine was performed by removing 90% of its length. Following a period of approximately 2 months, the animals presented excessive steatorrhea and severe cachexia. Construction of a valve using a local transposition flap within the intestinal lumen near the colon resulted in a detainment of weight loss and steatorrhea. The animals were kept under observation over a period of 4 months.

Animals↗
PubMed1983

Bronchodilatory effect of inhaled versus oral salbutamol in bronchial asthma.

The bronchodilator effect of salbutamol inhalation was compared with the oral administration of the drug in 10 patients with bronchial asthma. The study consisted of treating each patient for 4 consecutive days with: (1) a combined regimen consisting of a 2-mg tablet of salbutamol and 10 puffs of salbutamol inhalation (100 micrograms in each puff) given in pairs of two puffs every 20 min (regimen 1); (2) salbutamol inhalation (regimen 2); (3) salbutamol tablet (regimen 3), and (4) placebo, tablet and inhalation (regimen 4). The bronchodilator effect was assessed measuring the forced expiratory volume in 1 s, the forced vital capacity and the peak expiratory flow rate. The bronchodilator response was significantly greater on the inhalation alone and the combined regimen than on the oral and placebo regimens. The combined regimen showed a better although not significant bronchodilatory response than the inhalation regimen. We conclude that the inhalation treatment with salbutamol is superior to the oral route of administration in treating bronchial asthma and that the oral treatment has an added effect.

Administration, Oral↗
PubMed1982

Vectorcardiographic and hemodynamic correlation in chronic obstructive pulmonary disease.

Vectorcardiograms in 34 patients with chronic obstructive pulmonary disease and 30 normal people were analyzed with the aim of developing sensitive criteria for the detection of pulmonary artery hypertension. The pulmonary artery pressure was correlated with the known vectorcardiographic measurements of the area of the QRS loop and with two new linear measurements which reflect the QRS loop displacement of the right ventricular hypertrophy. The proposed linear vector-cardiographic and the QRS loop area criteria provided a sensitive means for the noninvasive approximate estimation of mean pulmonary artery pressure in patients with chronic obstructive pulmonary disease. Their sensitivity and specificity were proved to be considerable.

Adult↗