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Biomedical subjects

N Genton

Publications and source records attributed to N Genton.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Efficiency and limitations of Pickrell's anomyoplasty in treatment of postoperative incontinence in children with anorectal malformations (author's transl)].

Eight children with high or intermediate anorectal malformations and fecal incontinence after primary repair were operated according the Pickrell technique. In 3 patients, the result of the Pickrell plasty was clinically not sufficient and the opposite gracilis muscle was used in addition at a second operative session. The 8 children were studied clinically, radiologically, by electromyography and manometry. The results are presented in detail. All 8 patients had a good passive continence at rest, but an active physiological continence could not be achieved. This seems to be due mainly to the absence of the internal anal sphincter, but partially also to the incomplete or even lacking adaptation of the pulled through bowel, which showed a relative hyperactivity and did not function as a neorectal reservoir. Some therapeutic measures to overcome the problems due to the fact that we deal at the same time with smooth and with striated muscles are discussed in the limelight of the present study.

Adolescent↗
PubMed1979

Thoracopagus conjoined twins: radiological evaluation of one case.

Radiological study of conjoined thoracopagus twins. The digestive and biliary tracts, the urinary and cardiovascular systems have been examined. The problems and difficulties encountered in the various procedures and in the interpretation of their results are described.

Adult↗
PubMed1978

Endovesical transurethral electrostimulation in the rehabilitation of neurogenic bladder in children. 4 Years clinical experience.

4 years of experience in the rehabilitation of neurogenic bladders by endovesical electrostimulation (ES) with 31 children permits us to judge the value and limitations of this treatment. 8 children (26%) reacted favorably to treatment and acquired continence approaching normal. 12 children (38%) showed modifications of bladder-sphincter equilibrium, without acquiring socially sufficient continence. 10 children (33%) showed no response to treatment. In 1 child ES may have precipitated bladder decompensation. An analysis of clinical, manometric, and radiological results in comparison to the underlying pathology permitted us to define the contraindications to ES therapy, criteria which should in the future permit a more efficient selection of patients.

Adolescent↗
PubMed1978

Prepubertal XX male with profound physical and mental deficiency, retinitis pigmentosa and multiple congenital anomalies.

A unique case of a prepubertal XX male with profound mental and physical retardation, retinitis pigmentosa, ambiguous genitalia and multiple congenital anomalies is reported. His clinical, genetic, dermatoglyphic and histological findings are presented. This case could represent a new multiple congenital malformation syndrome. Theories on XX male aetiology are briefly discussed.

Abnormalities, Multiple↗
PubMed1975

Renal function in obstructive nephropathy: long-term effect of reconstructive surgery.

Renal function was studied in 24 children with chronic hydronephrosis and renal insufficiency. The follow-up period after reconstructive surgery was 1 to 12 years. Glomerular filtration rate (GFR) was assessed by the clearance of endogenous creatinine or inulin. Effective renal plasma flow was assessed by the clearance of PAH. Reconstructive surgery was performed during the first year of life in 12 out of 24 patients, between one and two years of life in 6 patients, and after two years of life in 6 patients. Three different patterns of evolution could be observed after relief of obstruction: (1) An improvement or a normalization of renal function only occurred in patients operated upon before one year of life. (2) A stabilization of renal function without normalization was observed in patients operated upon between one and two years of life. (3) A progressive deterioration of renal function towards terminal renal failure was observed in five out of six patients operated upon after two years of age. This deterioration could not be explained by recurrence of detectable urinary tract infection or urinary stasis. The changes in GRF in four patients with a solitary kidney followed the same pattern. We conclude that it is essential to correct severe chronic hydronephrosis associated with renal insufficiency before one year of age if a lasting improvement of renal function is to be expected.

Child, Preschool↗