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Biomedical subjects

N Ghaed

Publications and source records attributed to N Ghaed.

At least 37 records · Page 2Linked to original sources
PubMed1984

Importance of soft-tissue evaluation in hand and wrist trauma: statistical evaluation.

Four radiologists reviewed 197 hand and wrist radiographs to determine the usefulness of routine soft-tissue evaluation in the delineation of bony trauma. Soft-tissue changes at four sites in the lateral view were evaluated. Dorsal-hand fat-plane swelling was associated with second through fifth metacarpal fractures (p less than 0.01). Dorsal-wrist fat-plane swelling was associated with carpal fractures and wrist dislocations (p less than 0.01). Pronator and dorsal radial swelling were both associated with forearm fractures and carpal dislocations (p less than 0.01). Soft-tissue changes at five sites in the posteroanterior view were evaluated. Thenar swelling was associated with thumb metacarpal fractures and dislocations (p less than 0.01). Hypothenar swelling was associated with second through fifth metacarpal fractures and dislocations (p less than 0.01). Navicular fat-pad swelling was associated with carpal fractures (p less than 0.01) and strongly suggested a navicular fracture when present. Pararadial swelling was significantly associated with distal radial fractures (p less than 0.01), while paraulnar swelling was significantly associated with ulnar fractures (p less than 0.01). The lateral view of the hand and wrist is useful in compartmentalizing fractures to the hand, wrist, and forearm. Swelling in any compartment should lead to closer evaluation of all bony structures contained within that compartment. The soft tissues found in the posteroanterior view of the hand and wrist help further localize hand and wrist fractures. Additional views should be considered when significant swelling is present in the absence of an obvious fracture or dislocation. When more than one fat plane is unequivocally disturbed, protective immobilization with reexamination in 10 days is recommended.

Adipose Tissue↗
PubMed1984

A reevaluation of placental grading and its clinical significance.

Pregnancies complicated by preeclampsia or intrauterine growth retardation have an earlier and faster placental maturation than normal. This is demonstrated in a study of 1,096 obstetrical examinations of 473 non-diabetic mothers. It is recommended that a pregnancy demonstrating grade I maturational changes prior to 27 weeks, grade II changes prior to 32 weeks, or especially grade III changes prior to 34 weeks be followed clinically and ultrasonically for possible complications.

Female↗
PubMed1983

Comparative analysis of ultrasonographic methods of gestational age assessment.

Measurement of crown-rump length (CRL) is widely accepted as the most accurate method of gestational dating. The statistical accuracy of growth-adjusted sonographic age (GASA) determinations has been demonstrated to be similar. Ninety-six patients were prospectively examined by use of serial ultrasonography, and findings were evaluated to correlate CRL with a single biparietal diameter (BPD) obtained between 20 and 24 weeks of gestation, with GASA, and with accurate maternal dates. Growth-adjusted sonographic age was shown to be not as accurate as CRL and no more accurate than a single BPD obtained between 20 and 24 weeks or reliable maternal dates.

Anthropometry↗
PubMed1980

Serum thyroglobulin levels predict total body iodine scan findings in patients with treated well-differentiated thyroid carcinoma.

Forty-eight consecutive patients with treated thyroid carcinoma were studied with 131-I total body scans and serum thyroglobulin (hTg) levels. Serum hTg levels during thyroxine treatment accurately predicted scan results (chi square = 18.6, p < 0.001). All patients with negative scans (24 patients) had serum hTg levels (< 7 ng/ml whereas in patients with metastatic thyroid cancer (eight patients) they ranged from 11 to 690 ng/ml. In patients with iodine uptake confined to the thyroid bed (16 patients) serum hTg values ranged from 2 to 17 ng/ml. Serum hTg levels rose in patients with negative scans during hypothyroidism or after exogenous TSH suggesting that hTg levels are more sensitive than iodine scans in detecting residual thyroid tissue. Serum hTg levels could replace total body iodine scans in many patients with treated thyroid carcinoma.

Adult↗
PubMed1979

Assessment of a technique for scintigraphic monitoring of pulmonary aspiration of gastric contents in asthmatics with gastroesophageal reflux.

Ten asthmatics with gastroesophageal reflux had scintigraphic evaluation of gastropulmonary aspiration. Five mCi of Tc99m sulfur colloid diluted in 50 ml of isotonic saline were administered by nasogastric tube at bed time and the lungs were imaged the following morning. Imaging in 20 studies yielded no evidence of gastropulmonary aspiration. Scintigraphic evaluation has previously been reported to demonstrate gastropulmonary aspiration in some patients with gastroesophageal reflux and pulmonary disease. This study indicates that the technique may lack adequate sensitivity or that gastropulmonary aspiration in asthmatics with gastroesophageal reflux occurs in only a small subgroup of these patients or at infrequent intervals and is difficult to detect.

Adult↗
PubMed1978

Accumulation of 99mTc-diphosphonate in hepatic neoplasm.

Bone images revealed excessive accumulation of radionuclide within a lesion in the liver which was suspected to be a metastasis from a primary carcinoma in the gastrointestinal tract. A "doughnut sign" of the liver with 99mTc-diphosphonate is rare, and the possibility of specific tumor uptake of this nuclide should be kept in mind.

Adenocarcinoma↗
PubMed1978

Glucagon and diuresis in the treatment of ureteral calculi.

Intravenous glucagon and diuresis caused by diagnostic doses of sodium diatrizoate were used to treat 5 patients with ureteral colic and urographic findings consistent with partial obstruction by a ureteral calculus. Pain was relieved and the calculus passed within two hours in 4 patients and within eight hours in the fifth. No complications were noted.

Adult↗
PubMed1976

Low dose radioiodide thyroid ablation in postsurgical patients with thyroid cancer.

Sixty-four patients with well-differentiated carcinoma of the thyroid were treated with initial high (80 to 100 mCi) or low (less than 30 mCi) doses of I131 after bilateral subtotal thyroidectomy. A total of 36 patients in the various histologic categories were initially treated with the low dose of I131 (group 1), and a total of 28 patients were treated with the higher dose (group 2). Disease-free criteria were no visible tissue in the neck or body, a protein-bound radioactive iodine (PBI131) of less than 0.005 per cent per liter at seven days and/or whole body retention of less than 3 per cent at seven days. Of the patients receiving less than 30 mCi (group 1), 56 per cent with papillary carcinoma, 67 per cent with follicular carcinoma and 56 per cent with mixed carcinoma of the thyroid were rendered disease-free after this initial dose. Of the patients receiving the higher dose of I131 (group 2), 67 per cent with papillary carcinoma, 50 per cent with follicular carcinoma and 67 per cent with mixed carcinoma of the thyroid were rendered disease-free after this initial dose. Disease-free mean follow-up time was 5.17 years (group 1) and 5.82 years (group 2). There was no statistical difference in these mean follow-up times, nor was there a statistical difference in the net (total minus initial) dose of I131 needed to render the patient disease-free. These data demonstrate that low dose I131 therapy is as effective as the larger more routine doses of I131 given in this disease.

Adenocarcinoma↗
PubMed1974

Pitfalls in Tc99m polyphosphate skeletal imaging.

The quality of Tc-PP scans is best in younger patients. In all age groups quality is adversely affected by free TcO4-. This should be suspected if excessive background is present or marked accumulation is noted in the thyroid gland. Direct physician supervision of all studies is recommended. Symptomatic and roentgenographically positive areas may then be determined for special interpretative attention. Objects which attenuate activity should be removed or noted. Potential sources of superficial contamination (product spill, urine, saliva) must be known and considered when extraneous activity does not correlate with skeletal structures or clinical findings. Normal variations in skeletal uptake of Tc-PP include asymmetries between periarticular areas on the right and left, local increases due to physiologic calvarial thickening and uptake in persistently visualized sternal ossification centers. Apparent variations in the vertebral activity may be due to focal plane effects of rectilinear scanners. Hyperemia can cause diffusely increased Tc-PP localization in an entire extremity. This effect may completely obscure a lesion or obscure the extent of a lesion. Tc-PP excretion through the kidneys occasionally provides useful morphologic or functional information concerning the urinary tract which should be inspected on all scans. Abnormal soft tissue uptake occurs in a variety of conditions including healing wounds and some malignant tumors. A large percentage of patients over 40 years of age demonstrate localization of Tc-PP in the walls of the femoral vessels.

Adolescent↗