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Biomedical subjects

N Gheorghiţă

Publications and source records attributed to N Gheorghiţă.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The importance of the use of selenium in the role of an antioxidant in preventing cardiovascular diseases].

The evaluation of the results of the oxygen free radicals (RLO2) formation is a current subject in biology and medicine. The oxidative stress, which is the altering of the balance between the higher activity of oxygen and the enzymatic or nonenzymatic protection systems, may be one of the causes that starts and aggravates a disease. In this context, the supplementation of the diet with selenium, superoxide dismutase, vitamins A, C, E, is considered a primary prevention measure (for the apparently healthy persons) and a secondary one (for those with advancing forms of disease) that is both efficient and modern by utilization of some "drug-food" products. The transversal study realized on a group of 39 blood donors presence of the cardiovascular risk determined by the raising of the prevalence of some atherogenic factors (active smoking, hypercholesterolemia) which is also expressed by the lowering of the level of some oxidative stress indicators (glutathione peroxidase--GSH-Px < 0.139 moli/ml and catalase < 2.20 U/ml). The simultaneous low intake of selenium from the central drinking water supplies in the city of Iaşi (0.1-1 g/l) has permitted us to consider necessary the diet supplementation both with foods rich in vitamins with an antioxidant role and with specific medication with selenium, as a protective micro-element.

Adult↗
PubMedDate not supplied

[Glutathione and the redox index in different types of cellular oxidative stress. I. Acrylonitrile (ACN) poisoning].

The professional poisoning with acrylonitrile of some subjects induced a significant decrease of reduced glutathione (81.30%), redox ratio reduced glutathione/oxidized glutathione (90.74%) and "Benzi-redox index" (55.84%) but an increase of oxidized glutathione level (112.6%) as compared to normal controls (100%). This proves the occurrence, in time, of the cellular oxidative stress and/or were obtained.

Acrylonitrile↗