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N Ghilezan

Publications and source records attributed to N Ghilezan.

24 records · Page 2Linked to original sources

[Possibilities of cobalt therapy in bronchopulmonary cancer].

Cobaltotherapy was applied in 194 cases of bronchopulmonary cancer in the Oncologic Institute of Cluj-Napoca, during the 1967--1974 period. The mean survial was of 15 months, the results being influenced by the histologic type and locoregional extent apraised on the basis of the TNM classification proposed by the American Joint Committe for Cancer Staging and End Result Reporting. The mean survival after irradiation was of 9.7% and 5.1% at 3 and 5 years respectively. Standardization of the cases according to the TNM criteria showed the advanced stage of the patients referred for radiotherapy, proving a useful tool for establishing the prognosis and therapeutical indications. Next to the histological type and TNM category, the efficiency of radiotherapy is also influenced by the size and shape of the tumor, which conditions the irradiation technique. The central tumours or those of the upper lobes may be irradiated by small 150 cm2 beams and are the only ones that benefit by radical radiotherapy, the survival rate at 2 and 5 years being 12.3% and 7.6% respectively. In all the other cases the prognosis is more reserved, suggesting the necessity of associating chemotherapy or immunotherapy for improving the results.

Adenocarcinoma↗

Morphometric grading of laryngeal squamous cell carcinomas.

The authors have used the point counting method for the morphometric assessment of the histological aspect of laryngeal carcinoma. The results suggest that subjective histopathological grading tends to overestimate the tumor grade. The implications of these data for the prediction of prognosis and selection of therapy are briefly discussed.

Carcinoma, Squamous Cell↗