[Abscess-forming tuberculosis of the lymph nodes].
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Biomedical subjects
Publications and source records attributed to N Goebel.
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In 6 patients a hemispheric epidiaphragmatic shadow was observed in chest X-ray. It was located in the dorsolateral or dorsomedial aspect of the left diaphragm in 4, on the left diaphragmatic cupola in 1, and in the right cardio-phrenic angle in 1. In each case the shadow was caused by herniation of fat through the diaphragm. In one case a hernia of Morgagni was found on thoracotomy. In the other 5 patients the diagnosis of fatty herniation was made by computed tomography, which demonstrated the small diaphragmatic defect as well as the fatty nature of the mass. These 5 patients did not undergo surgery as the herniation caused no symptoms.
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Natural history of an aneurysm at the bifurcation of the left coronary artery is reported. A gradual increase in its size occurred over an 18-year period until it was a huge and partially thrombosed sac. It was associated with ectasia of the right coronary artery, aneurysms of the left subclavian artery and thoracic aorta, and calcified dilatations of the branches of the celiac trunk.
A patient with successful implantation of an internal mammary artery graft in the left anterior descending coronary artery complained of residual but different anginal pain after operation. Ischemia was demonstrated during a manual stress test. Angiography revealed anomalous origin of the thyrocervical trunk from the internal mammary artery. Angina and ischemia disappeared after the trunk was ligated.
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CT and ultrasound of the abdomen were retrospectively evaluated in 44 patients operated on colorectal cancers (18 colon, 26 rectal carcinomas) in detecting a recurrence suspected on biochemical, endoscopic or clinical grounds. CT is superior to ultrasound in detecting a recurrence (metastases of liver and lymph nodes, local recurrence, intra-abdominal recurrence of another localisation). CT is recommended as a routine examination in the follow-up of patients operated on colorectal cancers.
The effects of the antiaggregant substance ticlopidine and of the anticoagulant acenocoumarol on patency rates of aorto-coronary bypass grafts were compared in a prospective randomized trial. Ticlopidine, 250 mg b.i.d. was administered orally from the first postoperative day till angiography, while anticoagulation with acenocoumarol was initiated on the second to third postoperative day. Side-effects of ticlopidine were rare and patient management with the standard dosage of this drug was easier than oral anticoagulation. From an initial group of 166 randomized patients 149 completed the trial by coronary angiography three months postoperatively. The 78 patients in the ticlopidine group showed a compliance of 85%. The average prothrombin time in the 71 patients receiving acenocoumarol was 26.9%. Detailed statistical analysis of the two study groups revealed no reason to doubt the correctness of randomization. Coronary angiography showed an average patency rate per patient of 84% with ticlopidine and of 82% with acenocoumarol. This and various other measures of graft occlusion did not reveal any substantial difference in graft patency of patients receiving ticlopidine or acenocoumarol. It is concluded that ticlopidine may well be used instead of anticoagulants for prevention of postoperative occlusion of aorto-coronary bypass grafts.
In four patients muscle necroses were observed. In two patients these were caused by intraoperative positioning, in one by having worked with a pneumatic hammer and in one possibly by alcohol. CT showed hypodense areas in the affected muscles which were--in the state of subacute necroses--surrounded by hyperaemic borders. The diagnosis was confirmed by puncture or biopsy. After six months hypodense areas were still perceptible in the atrophic muscles of two patients.
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