PubMed HealthSearch

Biomedical subjects

N Goebel

Publications and source records attributed to N Goebel.

At least 127 records · Page 7Linked to original sources

[Surgical treatment of myocardial aneurysms. Indications and results].

The long term results of 95 left ventricular aneurysmectomies are presented. In 47 patients simultaneous aorto-coronary bypass surgery was performed. 53 patients presented preoperatively with congestive heart failure; 8 out of these died within the first postoperative month, while 5-year survival rate (actuarial method) was 52%. Two thirds of this patient group improved. None of the 42 patients without preoperative congestive heart failure died early. 5-year survival rate was 93% and subjective improvement was recorded in one half of this subgroup. Comparison of pre- and postoperative angiograms (40 patients) revealed an increase in left ventricular ejection fraction reflecting the removal of the non-contracting segment. The ejection fraction of the contracting segment of the left ventricle improved after aneurysmectomy, especially in patients with preoperative congestive heart failure. In conclusion, aneurysmectomy improves left ventricular function and the symptoms of heart failure; moreover, it prevents perforation of false aneurysms. Its effect on arrhythmias could not be determined conclusively. Angina may be improved by simultaneous aorto-coronary bypass surgery.

Angina Pectoris

[Abeurysm of the septum membranaceum].

Between 1968 and 1977 5000 angiocardiographies revealed an aneurysm of the membranous septum (AMS) in 20 patients. In 11 patients the AMS was accompanied by a usually minor ventricular septal defect, in 4 by aortic valve disease, in 3 by coronary heart disease and in the remainder by some other rare heart disease. The diagnosis of AMS was established by angiocardiography, but in 3 patients it was detected by echocardiography. In one case a sepsis lenta with cerebral embolization was observed.

Adolescent

[Coronary fistulae (author's transl)].

Three patients with coronary fistulae are described, including one patient with a rare coronary-pulmonary double fistula. The clinical features, diagnostic aspects and radiological signs are reviewed.

Adult

[Bi-ventricular endo-myocardial fibrosis (author's transl)].

Bi-ventricular endo-mycardial fibrosis was diagnosed in two European women. Clinically there was severe cardiac insufficiency in the presence of only moderate radiological cardiac enlargement. Haemodynamically there was restricted filling, but otherwise normal systolic ventricular function. The diagnosis depended on the angio-cardiographic demonstration of a small, globular left ventricular chamber with a tubular narrowed right ventricle with a thickened wall, particularly at the apex. In one patient the endo-myocardial fibrosis was also demonstrated by echocardiography.

Adult

[Large solitary aneurysm of the left coronary artery. Plain films and angiography (author's transl)].

The diagnosis of coronary aneurysms has for a long time been made at autopsy. After a general review of coronary artery aneurysms, a large aneurysm of the circumflex branch of the left coronary is described; this was diagnosed by selective coronary angiography and successfully treated by surgery. The results are compared with six other reported cases of pre-operatively diagnosed coronary artery aneurysms. Since complications, such as rupture, embolisation or infarction, are common in large coronary aneurysms, early diagnosis is desirable. An abnormal bulge of the cardiac contour or circular calcification within or at the edge of the cardiac shadow may be suggestive of the diagnosis.

Adult

[Aortic abnormalities in Marfan's syndrome].

Three different forms of aortic lesions in Marfan's Syndrome are demonstrated: 1. moderately severe aortic valve insufficiency due to sinus of Valsalva aneurysm; 2. severe aortic valve insufficiency due to aneurysmal widening of the ascending aorta; 3. an unusually wide dissecting aneurysm extending from the aortic root to the aortic bifurcation. A review of the current literature of the changes in Marfan's Syndrome is given. It is obvious that early diagnosis of the cardiovascular changes is important for the patient's prognosis, allowing the optimal time for surgical intervention to be chosen.

Adult