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N Grigorov

Publications and source records attributed to N Grigorov.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Guided punctures in the treatment of hepatic and perihepatic abscesses under ultrasonic control].

The authors discuss the possibilities of ultrasonic tomography and subsequent performance of purposeful punctures for establishing the precise diagnosis of hepatic and perihepatic abscesses. In most cases the method helps in revealing the cavities measuring no more than 1.5-2.0 cm. The indications are determined, as well as the techniques of topical treatment with the use of single and multiple punctures and prolonged percutaneous drainage. Seventy-three patients (32 with hepatic and 41 with perihepatic abscesses) underwent clinical examination. Topical therapy was applied in 21 patients with discovered hepatic abscesses, 17 of them recovered. Operations were avoided in 25 in a group of 34 patients with perihepatic abscesses (in 7 the abscesses were not identified). The success of this treatment is determined by exact diagnosis and precise manipulations.

Adult↗
PubMed1990

[Transcutaneous drainage of pancreatic pseudocysts].

The clinical study includes 76 pancreatic pseudocysts localized in the head (24), body (37), and tail (15). The effect of treatment by means of a single or repeated purposeful aspiration in ultrasonic control is discussed. Recovery occurred in 83.3% of cases with cysts measuring up to 5 cm, in 61.3% in those with cysts measuring from 5 to 10 cm, and in 11.1% of cases in which the cysts measured more than 10 cm. As the result of 15 draining manipulations of cysts which were irresponsive to aspiration (9 of them measuring from 5 to 10 cm and 6 larger than 10 cm) complete recovery occurred in 13 cases. The authors discuss the indications for single, two, and many punctures on basis of a complex appraisal of the gland, the size and type of the cyst, and the cytologic results. The indications for percutaneous drainage, the period and techniques of its performance and preliminary and postmanipulation treatment with drugs are determined and the occurring complications are shown.

Adult↗
PubMed1987

[Differential diagnosis of jaundice].

Patients with jaundice and hyperbilirubinemia over 34 mumol/l have been examined by different methods in order to assess the diagnostic value of the methods. 340 patients were examined clinically and by laparoscopy, 168 patients and 92 healthy persons were examined by 10 laboratory indices, 639 patients--by ultrasonography, 95 patients--by scintigraphy, 116 patients--by computer tomography, 83 patients--by endoscopic retrograde cholangio-pancreatography (ERCPG), 17 patients--by percutaneous transhepatic cholangiography (PTC), 70 patients--by directed liver biopsy. In the patients with cholestasis the 5'-nucleotidase, alkaline phosphatase, glutamyl transpeptidase (lipoprotein X is positive in 92% of the patients) and cholesterol are increased most. The extrahepatic obstructions are diagnosed by ultrasonography in 94.8% of the patients (the biliary ducts are dilated), in 88.7% of the patients the localization of the obstruction and in 74.7% of the patients the cause of the obstruction are found. In parenchymal jaundice the sonography reveals the disease which has caused jaundice in 62.1% of the patients. The scintigraphy gives correct diagnosis in 50% of the patients with hepatitis and jaundice, in 78% of the patients with cirrhosis and jaundice and in 87.5% of the patients with liver cancer. The computer tomography reveals the obstructive jaundice in 94.7% of the patients and the focal processes in the liver in 96.7% of the patients. The ERCPG gives a clear picture of the biliary ducts in 72.28% and of the pancreatic duct in 83.13% of the patients with jaundice, simultaneously the biliary and the pancreatic ducts--in 45.78% of the patients and correct diagnosis in 83.1% of the patients examined.(ABSTRACT TRUNCATED AT 250 WORDS)

Cholestasis, Extrahepatic↗
PubMed1986

[Echographic diagnosis of hypernephroid cancer].

A total of 28 hypernephroid tumours have been diagnosed within a period of 32 months. The data from echographic, intravenous urography, computer tomography and thin-needle aspiration biopsy and renovasography were compared in the patients studied. Two basic variants of echographic picture have been described. It has been concluded that the combination of abdominal ultrasound tomography with thin-needle aspiration biopsy is a valuable method for the diagnostics of hypernephroid cancer. Computer tomography proved to be appropriate in solving the problem of operability, renovasography--pre-operatively, and the rest of the methods--in suspected and undistinguished echographic evaluations.

Adult↗
PubMed1986

[Echography with fine-needle aspiration biopsy of the pancreas].

The results from 116 echographic investigations of 74 females and 42 males with confirmed pancreas carcinoma are discussed, the patient aged from 27 to 80 years. The diagnosis has been confirmed operatively in 92, at necropsy--in 16 and clinically--in 8. Thin needle aspiration biopsy (TAB), under echographic control was performed to 47 patients. The results were compared with the results obtained by computer tomography, endoscopic retrograde cholangiopancreatography and selective angiography. It has been established that the combination of echography with TAB results in 81.9% accuracy of the method, in 6% presumed neoplastic diagnosis and in 22.1% the diagnosis was not made. The results are significantly better than those obtained only by echography (p less than 0.01). A diagnostic scheme for the timely diagnosis of pancreatic cancer is presented.

Adult↗
PubMed1985

[Diagnostic value and the criteria for abdominal echography in cancer of the gallbladder and bile ducts].

Sixty one patients were studied during a three-year clinical investigation: 39 patients with cancer of gallbladder and 22 with cancer of biliary ducts. The diagnostic values of echography in those diseases was assessed. The method proved to be sensitive in 84,6 per cent in cancer of gallbladder, with specificity in 94,6 per cent and accuracy in 90,5 per cent and in cancer of biliary ducts, with the exception of papilla of Vater, those values were 66,6, 96,2 and 95,5 per cent respectively, and in papilla--28,6, 98,8 and 93,7 per cent. The good diagnostic values of the method in cholestasis and the place of biliary stop is stressed upon. Various echographic images of cancerous alterations of gallbladder and biliary ducts are described.

Abdomen↗
PubMed1982

[Parallel laparoscopic and echographic studies in hepatobiliary diseases].

Parallel laparoscopic and echographic examinations were performed to 382 patients with hepatobiliary diseases. Out of 201 patients with diffuse diseases of the liver, accurate diagnosis of liver cirrhosis was laparoscopically made in 98.4 per cent, and echographically in 85.6 per cent, in case of chronic persistent hepatitis in 100 per cent and 77.4 per cent resp. (the differences being statistically significant). Accurate diagnosis in a higher percentage was also laparoscopically made in chronic active hepatitis and liver steatosis as compared with the echographic method, the differences being statistically insignificant. In 134 patients with focal liver diseases, the accurate diagnosis of liver metastases was laparoscopically made in a higher percentage (in 92.5%, echographically in 88.75%) but in carcinoma of the gallbladder--echographically, the differences being statistically insignificant. In case of primary carcinoma and cystic formations of liver the potentialities of both methods are almost identical. Liver tuberculosis is only diagnoses by laparoscopy and liver biopsy.

Biliary Tract Diseases↗
PubMed1982

[Ultrasonic studies of the abdominal organs. II. Its diagnostic value in liver diseases].

Five hundred fifty three patients with diffuse and focal liver processes were examined via ultrasound tomography, with confirmed diagnosis by punch biopsy according to Mengini (23), laparoscopy (437), laparotomy (58), at necropsy (30) and with clinical accurate diagnosis in liver stasis (5). Accurate echographic diagnosis was made in 65.9 per cent of chronic hepatitis (from 88 patients), in 68.9 per cent of liver cirrhosis (from 228 patients), in 81.8 per cent of liver steatosis (from 33 patients). In 71 patients with liver cirrhosis and ascites the accurate diagnosis was made in 89.3 per cent. The coincidence between ultrasound and morphological diagnosis in metastatic liver carcinomas in 80.2 per cent (from 91 patients), in primary--72.2 per cent (from 18 patients) and in echinococcus cysts--96,3 per cent (from 82 patients). Ultrasound tomography has undoubted diagnostic value in diffuse and focal solid and cyst formations of liver in particular. The results obtained, for the proper interpretation, are necessary to be compared with those from the other investigation methods and the clinical data in the process of making the final diagnosis.

Abdomen↗