PubMed Health⌕ Search

Biomedical subjects

N Gruber

Publications and source records attributed to N Gruber.

26 records · Page 2Linked to original sources

Three-year echocardiographic follow-up study on canoeist boys.

The echocardiographic parameters were followed for 3 years in 15 boys aged 13 years on average, who were beginning competitive canoe race training, and were compared with the corresponding data on 17 boys of the same age who did not take part in sports. As compared to non-sporting boys the 13-year-old canoeist boys had a larger left ventricular end-diastolic diameter (46.13 +/- 4.64 mm vs 44.35 +/- 3.06 mm), a thicker left ventricular posterior wall (7.47 +/- 0.74 mm vs 6.47 +/- 1.18 mm) and particularly a thicker interventricular septum (8.33 +/- 1.18 mm vs 7.59 +/- 1.6 mm) just after they began sport, in spite of the fact there were no significant differences between the two groups in age, height, weight and body surface area. The preexisting difference in left ventricular hypertrophy between the two groups increased significantly during the 3-year follow-up period. The thickness of the left ventricular posterior wall in diastole increased to 9.20 +/- 1.01 mm vs 8.24 +/- 0.83 mm (p = 0.006), and that of the interventricular septum to 10.73 +/- 1.58 mm vs 9.59 +/- 1.18 (p = 0.025). The hypertrophic index and the left ventricular mass corresponded to the data given above (9.97 +/- 1.25 mm vs 8.91 +/- 0.94 mm, p = 0.01; and 261 +/- 50.7 g vs 202.83 +/- 45.8, p = 0.002, respectively). The canoeist boys had a slightly larger aortic root diameter at the beginning, and this difference increased and became more significant during the 3 years (29.4 +/- 2.39 mm vs 27.18 +/- 1.88 mm, p = 0.006). There were no significant differences between the two groups in the size of the left atrium, the fractional shortening of the left ventricle and the calculated ejection fraction and stroke volume.

Adolescent↗

Comparative echocardiographic studies in leading canoe-kayak and handball sportsmen.

Echocardiographic data on 21 top-grade kayak- canoeists and 16 top-grade handball players are compared. While the end-diastolic and end-systolic diameters as well as end-diastolic and end-systolic volumes did not appreciably differ, the posterior wall and particularly the interventricular septum both in diastole and systole were significantly thicker in kayak- canoeists than in handball players. Also the left ventricular mass was considerably greater in the former group. The differences were even more striking when the parameters in question were calculated in relation to 1 kg body weight, 1 m-2 height and 1 m2 body surface area. Since the members of both groups were competitors at international level, it can be assumed that the differences are due to the different degree of strain placed on the heart in these sports.

Adult↗

The heart in acromegaly: an echocardiographic study.

We used echocardiography to study anatomic and functional changes of the heart in 25 patients with acromegaly. Asymmetric septal hypertrophy was found in 10 patients, in the range of 12 to 30 mm, with an average of 16 mm. The degree of septum-thickness was severe in 1 case, marked in 5 cases and mild in 4 cases. Concentric left ventricular hypertrophy was present in 1 patient. In 8 patients the left ventricle was normal and left ventricular dilatation of more than 60 mm was present in 6 cases. Except in one patient, the ejection fraction was decreased in the dilated group, indicating diminished myocardial contractility. The growth hormone level was higher in patients with left ventricular hypertrophy as compared to those patients with normal or dilated left ventricles. In acromegaly primary myocardial hypertrophy may be related to the growth hormone level.

Acromegaly↗

Real-time ultrasound observation of breathing and movements in the fetal lamb.

In seven pregnant ewes with catheters chronically implanted in the fetus, real-time ultrasound observations of fetal breathing and body movements were correlated with direct measurements of fetal arterial and tracheal pressures, heart rate, and intrauterine pressure. There was excellent correlation between the ultrasound record of fetal breathing and recordings of intratracheal pressure changes even when breath amplitude was low or frequently was high. Fetal body movements (stretches, rolls, kicks) were observed during both breathing and nonbreathing periods; vigorous movements were accompanied by rapid deflections of the amniotic and tracheal pressure traces. Movement was frequently accompanied by transient increases or decreases in heart rate. The results indicate that real-time ultrasound is an accurate method of observation of fetal movement in pregnant sheep and is particularly valuable when combined with direct measurements of fetal physiologic parameters.

Animals↗