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N Gurusinghe

Publications and source records attributed to N Gurusinghe.

4 recordsLinked to original sources

Granulomatous angiitis of the central nervous system: a case with recurrent intracerebral haemorrhage.

A 43-year-old man with a history of radiculomyelopathy developed recurrent intracerebral haemorrhage confirmed by CT brain scan. Cerebral angiography and systemic investigations showed no underlying cause for the haemorrhage. Cerebral biopsy at the time of evacuation of a haematoma revealed granulomatous angiitis. This condition may be responsive to steroids and should be considered in cases of intracerebral haemorrhage of obscure origin.

Adult

The use of intraventricular vancomycin in the treatment of CSF shunt-associated ventriculitis.

Ten cases of shunt-associated ventriculitis treated with intraventricular vancomycin are described. Eight were cured of their infection, one of these without shunt removal, though this failed in another instance. There were no toxic or untoward effects except in one case, where intravenous administration of vancomycin produced a histamine-like reaction. Intraventricular vancomycin, preferably combined with oral rifampicin, should be considered in cases of intractable or problematic shunt-associated ventriculitis due to Gram-positive organisms.

Cerebral Ventricles

Stab wounds.

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Adult