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N H Larsen

Publications and source records attributed to N H Larsen.

6 recordsLinked to original sources
PubMed1997

[Heyde syndrome].

Since Heyde in 1958 suggested the association of aortic stenosis and significant gastrointestinal bleeding, the syndrome has been a matter of debate. After analysing the literature it is concluded 1) that a prospective well designed study is needed, but the Heyde syndrome seems to exist, since the gastrointestinal bleeding caused by angiodysplasia ceases after valve replacement in spite of the fact that the angiodysplasia remains, 2) that the cause of the association between aortic stenosis and bleeding from angiodysplasia is still uncertain, but impaired aggregability of thrombocytes does not seem to be the explanation and 3) that the treatment should be replacement of the stenotic aortic valve by either a mechanical or biological valve.

Angiodysplasia↗
PubMed1994

[Long-term carrier state of methicillin resistant Staphylococcus aureus after hospitalization].

In Denmark, strains of methicillin-resistant (MR) Staphylococcus aureus constitute less than 0.1% of all S. aureus isolates and are often acquired abroad. A strain of MR S. aureus phage type 77+ was isolated from a patient, who had been hospitalized in a Portuguese hospital three months earlier. In Denmark, the patient had been admitted to a private clinic for replacement of the aortic valve and a coronary bypass operation. The strain did not produce detectable soluble coagulase, and it was multiply resistant, including resistance to gentamicin, tetracycline, erythromycin, and rifampicin. It was probably non-invasive. Thirty-seven members of the staff were screened for MR S. aureus with negative results. The patient was treated with chlorhexidine to eliminate carriage, but, eight weeks after treatment, he was still colonized. Thus, in the current epidemiological situation in Denmark, it is important to take into consideration that carriage of MR S. aureus may last several months. We therefore suggest, that specific guidelines for hospital hygiene should be upheld not only for patients, who are transferred directly from hospitals in other countries, but also for patients, who have been hospitalized abroad within the last three to six months.

Aged↗