Tests of four baits for oral vaccination of dogs against rabies in Tunisia.
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Biomedical subjects
Publications and source records attributed to N Haddad.
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OBJECTIVE: To provide an inexpensive and extensive in vitro fertilization (IVF) service for the Mersey Region, United Kingdom. DESIGN: Twenty-four transport IVF patients treated in two district general hospitals using the central university laboratory as co-ordination point for treatment schedule and embryology. Outcomes were compared with 26 control patients treated in the central unit. SETTING: Royal Liverpool University Hospital, a central IVF unit, and two district general hospitals in the Mersey Region. PATIENTS: Fifty patients under 35 years of age with irreversible tubal damage selected and treated by IVF, half in the central unit and the other half in two district general hospitals. MAIN OUTCOME MEASURES: Pregnancy rate (PR) in the different centers. RESULTS: A PR of 42.3% per cycle in the peripheral hospitals compared with 30.7% per cycle in the central unit. CONCLUSION: Transport IVF is an inexpensive and feasible alternative to standard IVF in a central unit for patients without access to central units.
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We have vaccinated with an inactivated experimental vaccine, Rabi Rabta, prepared in lamb brain 52 dogs from the field in Tunisia and we tested by recommended serological methods the production of specific antibodies. The animals (35) received a boost injection after one year and the control of the immunological response was done on the same way after one month. This work done on 27 dogs showed very low serological data. A comparable batch of 42 dogs was immunised with a commercial vaccine with the same procedure; the results obtained from 17 dogs were not very different. This is apparently in contradiction with the success obtained by the National Program against Rabies launched in Tunisia since 1982.
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Three hundred and twenty young children were injected with Bacillus Calmette-Guerin (BCG) saline, or with one of the mycobacterial cytoplasmic antigens related with Mycobacterium leprae. At an appropriate time thereafter they were tested for dermal hypersensitivity to the antigens and for reactions to lepromin. Whereas all the antigens induced cell-mediated immunity, the incidence and intensity of late response to lepromin were significantly reduced in children preinjected with the cytoplasmic mycobacterial antigens, as contrasted with increased lepromin reactivity in the BCG group and with the findings in saline-injected children.
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The Tunisian experience in a recent field rabies control program is described. The Tunisian program emphasizes control of rabies in dogs, the essential source of virus for other animals and humans. The different phases of this program to reduce and eliminate canine rabies by systematic vaccination of accessible dogs and removal of other dogs are described, recent results are presented, and future plans are discussed in light of these results.
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