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Biomedical subjects

N Hanamura

Publications and source records attributed to N Hanamura.

At least 19 recordsLinked to original sources
PubMed1992

[A clinical study of the significance of the gradient between feeding arterial tissue polypeptide antigen (TPA) and draining venous TPA in assessing the risk for recurrent breast cancers].

The incidence of postoperative recurrence of primary breast cancers in 73 patients was correlated with the blood levels of tissue polypeptide antigen (TPA) in peripheral veins (V-TPA), feeding arteries (A-TPA), draining veins (V-TPA) and the gradient between the TAP levels in draining veins and feeding arteries (V-A TPA). With progression in the stage of the cancers, all parameters were increased. In stages II and III, the mean level of V-TPA was significantly higher than the mean level of A-TPA (p less than 0.05). In each stage, each parameter was increased in the patients with recurrences when compared with the levels in the patients with no recurrences. In patients with V-A TPA gradients greater than 30 U/L, the rate of recurrence was significantly higher when compared with patients with gradients less than 30 U/L (p less than 0.05). The clinical significance of this finding is that patients with V-A TPA gradient greater than 30 U/L should be closely followed because of the increased risk of recurrences.

Breast↗
PubMed1991

B-Z transition of poly(dG-m5dC) induced by binding of Lys-containing peptides.

Effects of oligopeptides containing Lys residues on the conformation of poly(dG-m5dC) have been investigated by circular dichroism spectroscopy. Lys-Ala-Lys (KAK) and its longer analogs with Lys-Ala repeats are found to convert the B-form polynucleotide to the Z form very efficiently. The ability to induce the B-Z transition is characteristic of alternating Lys-Ala sequences and increases exponentially with increasing number of the repeats. The heptapeptide KAKAKAK has an ability comparable with that of spermine, one of the most effective inducers hitherto known. The present results provide the first example of the B-Z transition of poly(dG-m5dC) induced by peptide binding.

Alanine↗
PubMed1989

[Study on fatigue toughness of dental materials. 1. Compressive strength on various luting cements and composite resin cores].

In this study, we investigated compressive strength of various luting cements and composite resin cores in both dry and wet condition, and then influences of repeating load on compressive strength in wet condition of distilled water at 37 degrees C. As frequency of repeating load increased, compressive strength of all materials decreased. It means that the repeated load cycling test used in this study is adequate for evaluating durability of various dental materials. The results were as follows: 1. In the condition of no loading in both dry and wet condition, resin cement indicated the highest compressive strength of all cements examined and was followed by glass ionomer cement, zinc phosphate cement and polycarboxylate cement. Glass ionomer cement was notably influenced in wet condition. 2. After 10,000 cycles of loading in wet condition, resin cement indicated the highest compressive strength again and was followed by glass ionomer cement, polycarboxylate cement and zinc phosphate cement. In particular, compressive strength of zinc phosphate cement decreased remarkably. 3. In the condition of no loading, visible light-cured composite resin core was superior to chemical one. Visible light one was notably influenced in wet condition. 4. After 10,000 cycles of loading, visible light-cured composite resin core was superior to chemical one.

Composite Resins↗
PubMed1989

[Study on composite resin cores. Part 2. Effect of pressing composite resin].

In this study, we investigated effects of pressing in building composite resin cores on compressive strength, retention of prefabricated post and sealing ability. 1. Compressive strength increased by pressing in composite resin cores. 2. Prefabricated post to the retentive forces was not influenced by pressing, but increased when bonding agent was used. 3. Pressing was very effective to improve sealing ability of composite resin to tooth structure. 4. Sealing ability of light-cured composite resin was not influenced by pressing but by curing types of bonding agent.

Composite Resins↗
PubMed1989

[Effect of soft laser on pain].

Two kinds of semiconductor laser, STOMA-LASER and Four-Luck, were used for patients having pain in the mouth and their effective rates were compared in 93 patients (133 cases). As a result, the following results were obtained. 1. The effective rate was 70.7% at the stage just after radiation. 2. Age, sex and oral hygiene were not significant for the effective rate. 3. The kinds of diseases were remarkably significant. 4. The kind of apparatus did not play any role in the effective rate as a whole, but was significant for the kinds of disease.

Facial Pain↗
PubMed1989

[Composite resin cores. Part 1. Comparison of various composite resin cores].

This study evaluated compressive strength, sealing ability and tensile bond strength of various materials of composite resin cores. 1. Compressive strength of the various materials, after they were placed in air for 24 hours, underwent thermal cycling testing, or were soaked in water for 2 weeks, ranged from 2000 kgf/cm2 to 2900 kgf/cm2. 2. The sealing ability after thermal cycling testing and being soaked in water for 2 weeks varied among the materials. 3. The bond strength of all composite resin core materials to dentin was less than 50 kgf/cm2. 4. In this study, no relationship was found between sealing ability and tensile bond strength.

Composite Resins↗
PubMed1989

[The report of the 12th and 13th clinical practical training of the Tsurumi University School of Dental Medicine].

This report concerns the state of the patients and the progress of the 12th and 13th clinical practical training. A questionnaire was carried out with the trainees of the 13th clinical practical training and their leaders. Consequently it was learned that a trainee was in charge of ten patients on the average a year. He was able to complete the treatments of 3.5 patients, but was obligated to discontinue them for 1.4 patients, while handling over treatments for 5.2 patients to the next year's trainees or doctors. The progress of the clinical practical training was slow during the first 9 months but the pace increased rapidly during the last 3 months. The results of the questionnaire showed 37% of the trainees were satisfied with the present clinical practical training, but 17% of the trainees were not satisfied. On the other hand 15% of the leaders were satisfied with it, but 48% of the leaders were not satisfied.

Education, Dental↗
PubMed1987

The usefulness and significance of naso-pharyngo-laryngo-tracheal fiberscopy in thyroid surgery.

The authors conducted naso-pharyngo-laryngo-tracheal fiberscopic examinations before and after thyroid surgery. Preoperative examination included an inspection of vocal cord movement, the compression and deformity of the trachea caused by goiters, changes in the color of the tunica mucosa tracheae, and the presence of tumorous invasion. Postoperatively, this method was employed primarily to determine the presence of recurrent laryngeal nerve paralysis, changes in the tracheal mucosa caused by manipulations in thyroid surgery and in cases in which surgery involved the tracheal wall, and to inspect the treated condition at the original tracheal site and detect the presence of possible recurrences. The manipulations can be easily carried out, causing little pain, and the procedure is economically feasible. Since it can provide more useful information than any other examination method, the active use of endoscopic examination by surgeons themselves at numerous facilities would appear desirable.

Endoscopy↗
PubMed1986

[A case of bilateral metastatic breast carcinoma from gastric carcinoma].

The patient was a 48-year-old woman who had undergone radical surgery for gastric carcinoma in 1981. Seventeen months after the operation, recurrence of gastric carcinoma at the anastomotic stoma was found, and total gastrectomy was performed. Fourteen months after the second operation, she was revealed to have bilateral breast tumors and underwent exploratory excision. Histological examination suggested primary malignant tumor of the breast. Bilateral standard radical mastectomy was done seven days after the excision. Final histological examination revealed metastatic breast cancer originating from the stomach. She died from general metastasis seven months after the radical mastectomy in spite of adjuvant immunochemotherapy.

Adenocarcinoma, Mucinous↗
PubMed1986

[RI angiography with 99mTc and 201T1-chloride scintigraphy in determining the effectiveness of intra-arterial infusion in chemotherapy of locally advanced and recurrent breast cancer].

Eleven patients with local advanced and recurrent breast cancer were treated preoperatively with intraarterial infusion of chemotherapeutic agents. After the treatment, nine patients underwent radical mastectomy. RI angiography with 99mTc is a useful procedure for determining the correct position of the tips of an inserted cannula. The results of 201Tl-chloride scintigraphy have been found to be closely consistent with the results of the resected specimen histologically. Therefore, 201Tl-chloride scintigraphy is also a quite useful procedure for determining the effects of intraarterial infusion in cancer chemotherapy.

Adult↗