Biomedical subjects

N Heye

Publications and source records attributed to N Heye.

39 records · Page 3Linked to original sources

PubMed1989

[Congenital ependymoma. Case report and immunohistochemical studies].

Reported in this paper is a congenital ependymoma in an 23-week old foetus. The neoplasm was well vascularised and contained typical ependymal rosettes. The tumour cells did not react with GFAP-antiserum. They reacted weakly with neuron-specific enolase and vimentin and exhibited strong antigenicity with S-100-protein-antiserum. Cytokeratin antigen was recordable from some tumour cells. The tumour was sufficiently mature for classification as ependymoma. Immunohistochemical findings suggested possible ectodermal origin of the tumour cells.

Brain Neoplasms↗

PubMedDate not supplied

Superficial siderosis of the central nervous system.

We report on three patients with superficial siderosis of the central nervous system. The main clinical findings were progressive dementia, hearing loss and ataxia in combination with repeated xanthochromia of the cerebrospinal fluid. Diagnosis was made in one patient with magnetic resonance imaging (MRI), which showed a hyperintense rim around the surface of the cerebellum and the spinal cord. In the two other cases necropsy disclosed superficial iron and hemosiderin deposits on the surface of the brain. The etiology either was idiopathic or secondary to chronic intracranial bleeding by an angioma or after multiple head injuries. Superficial siderosis should be taken into account as one reason for dementia.

Journal Article↗

PubMedDate not supplied

Acute multifocal motor neuropathy with early spontaneous recovery: a distinct syndrome from Guillain-Barré syndrome?

We describe a case of acute multifocal motor neuropathy with normal sensory conduction studies in the nerve segments of severe motor conduction block. Antiganglioside antibodies were not detected in serum and the patient recovered spontaneously. The clinical picture and course of time of the illness allowed the diagnosis of a Guillain-Barré syndrome (GBS). The electrophysiological findings closely matched the typical findings of chronic multifocal motor neuropathy with persistent conduction block. From these similarities, we conclude that acute and chronic forms of acquired demyelinating motor neuropathies have to be accepted as variants of acute GBS and chronic inflammatory demyelinating polyneuropathy (CIDP), respectively. We suggest that the conduction block cannot always be attributed to antiganglioside antibodies, as chronic cases without antiganglioside antibodies have also been reported and further elevation of antibody titres has been seen after spontaneous recovery.

Aged↗