Biomedical subjects

N Horesh

Publications and source records attributed to N Horesh.

22 records · Page 2Linked to original sources

PubMedDate not supplied

Psychosocial diagnosis in psychiatrically hospitalized adolescents.

This study examines the relevance of a psychosocial diagnostic system developed by the World Health Organization (WHO; International Classification of Diseases [ICD] 10 axis V) for psychiatrically hospitalized inpatient adolescents and assesses the reliability of semistructured interviews for making these psychosocial diagnoses. Seventy-one consecutive patients admitted to an adolescent unit and their parents were interviewed. The semistructured interviews were derived from the criteria for each psychosocial (axis V) diagnosis. Inter-rater and test-retest reliability were measured for both child and parent interviews on a subsample of 57 and 25 subjects, respectively. Results showed high inter-rater reliability (kappa = 0.8 to 1.0). Some test-retest reliabilities were high and others were low (kappa = 0.4 to 1.0). Parent-child agreement was erratic (kappa = 0.2 to 0.7). All of the psychosocial diagnostic entities were common and relevant to our patient population. We conclude that it is possible to make reliable and relevant psychosocial diagnoses in severely ill adolescents.

Adolescent↗

PubMedDate not supplied

The treatment of kleptomania with serotonin reuptake inhibitors.

Kleptomania is characterized by an irresistible impulse to steal objects not needed for personal use or for their monetary value. Several recent case reports have shown that Serotonin Specific Reuptake Inhibitors (SSRIs) could be effective in the treatment of kleptomania just as it is in other obsessive-compulsive spectrum disorders. We report five cases of kleptomania patients who were successfully treated with fluoxetine or paroxetine in combination with a psychotherapeutic intervention. In one case, the discontinuation of the medication repeatedly led to the resurgence of the kleptomanic behavior. Our case series illustrates the effectiveness of SSRIs in kleptomania. It thus supports the assumption that this syndrome involves a dysfunctional serotoninergic mechanism.

Adult↗

PubMedDate not supplied

Alexithymia, affect intensity and emotional range in suicidal patients.

BACKGROUND: Although negative affect in general has been widely associated with suicide, the role of specific emotions and affect features in depression and suicidality is unclear. This study examined the potential of three major components of the affect structure as predictors of suicidal behavior. METHODS: Twenty suicidal depressed (SD) inpatients were compared with 20 nonsuicidal depressed (NSD) inpatients and 20 healthy controls for alexithymia, emotional range (ER; i.e. variety of emotions experienced by the subjects) and affect intensity (AI; i.e. the intensity of their emotional responsiveness). RESULTS: Both the SD and the NSD patients had a narrower range of emotions, a stronger AI and a higher degree of alexithymia than did the healthy controls. No differences were found between the scores of the two inpatients groups. CONCLUSIONS: The three affect components examined (alexithymia, AI and ER) did not prove to represent sensitive predictors of suicidal behavior. Hopelessness and depression severity were found to be more reliable in the prediction of suicidal risk. We discuss the implications of this study, particularly the possibility of early detection and intervention in patients at risk.

Adult↗

PubMedDate not supplied

Long-term lithium prophylaxis in recurrent unipolar depression. A controversial indication?

The authors assessed results obtained with long-term lithium maintenance in a group of 33 recurrent unipolar patients, followed regularly in the outpatient clinic of the Chaim Sheba Medical Center for 1-15 years. They analyzed changes of frequency, severity and duration of depressive relapses, rate and duration of hospitalization, suicidal ideas or attempts, and various assessments of outcome. A significant reduction was found on all indices during lithium management as compared to before lithium treatment, attesting to the efficacy of long-term prophylactic lithium in recurrent unipolar depression. These results are discussed and compared with those from other reports.

Depressive Disorder↗