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Biomedical subjects

N Hoshimiya

Publications and source records attributed to N Hoshimiya.

At least 19 recordsLinked to original sources
PubMed1995

A clinical trial of therapeutic electrical stimulation for amyotrophic lateral sclerosis.

This paper describes the effects of therapeutic electrical stimulation (TES) on the wasting muscles in a patient with amyotrophic lateral sclerosis. The patient is a 47-year-old male, and he has a history of progressive muscle weakness and atrophy, affected more in the right side. Percutaneously indwelling intramuscular electrodes were implanted to the affected muscles in the right upper and lower extremities but no electrode in the corresponding left region. Within a month of TES therapy, a rapid improvement of extremity motion appeared in the TES treated side. Long-term application of TES more than 3 months increased the strength of the muscle which had been evidently weaker than the non-treated side. CT findings of both the upper and lower extremities with TES therapy showed an increase in the density and a reduction in the moth-eaten image. An increase in the thickness of the muscles was also observed in the TES treated side while deterioration was observed in the muscles on the non-treated side.

Amyotrophic Lateral Sclerosis↗
PubMed1995

Control of thumb movements: EMG analysis of the thumb and its application to functional electrical stimulation for a paralyzed hand.

This paper describes the control of thumb movements by functional electrical stimulation (FES). In order to determine stimulation data of thumb muscles, activities of nine thumb muscles and the palmaris longus were analyzed in normal subjects by averaging their EMGs. In this analysis, it was found that well coordinated contractions of these thumb muscles were required for finer movements and precise positioning of the thumb. Based upon this analysis, several standard stimulation data for the thumb muscles were programmed and stored into a computer-controlled FES system. Input of the threshold and maximum stimulating voltages for individual thumb muscles of normal subjects to the system enabled automatic creation of stimulation data for each subject. The thumb movements of the normal subjects induced by these data were very smooth and their trajectories were reproducible. In addition, precise thumb positioning and joint stability were easily obtained. These standard stimulation data for the thumb muscles were also applied to FES control of a C4 quadriplegic. The controllability of the thumb movements was improved and the reliability of hand tasks achieved by FES was increased.

Adult↗
PubMed1994

Telemedicine using mobile satellite communication.

With a view to providing paramedical care within moving vehicles, a telemedicine technique using mobile satellite communication was proposed. With this technique, the diagnosis from a specialist and the emergency care under his/her instructions would be available on the spot without unnecessary delay. The characteristic problems of this technique were identified as: channel capacity, size of the system, reliability of vital sign transmission, real-time operation and electromagnetic interference. Measures against these problems were devised, and their effectiveness was analyzed. A data format was designed and an experimental system was developed. The system can simultaneously transmit a color image, an audio signal, 3 channels ECG and blood pressures from a mobile station to a ground station. It can transmit an audio signal and error control signals from a ground station to a mobile station in a full duplex mode. Fundamental transmission characteristics were measured in a fixed station. Finally, experiments of medical data transmission were conducted with a navigating ship and an aircraft flying an international route. The measured threshold values of C/N(o) to guarantee satisfactory data reception were well below the lower boundary of C/N(o) of the communication link. Consequently, the feasibility of this technique was verified.

Aircraft↗
PubMed1994

Electrophysiological studies of the biceps brachii activities in supination and flexion of the elbow joint.

Activities of the biceps brachii (long head: BiL, short head: BiS) on the elbow joint were studied using an electrical neuromuscular stimulation (ENS) and an electromyography (EMG). In ENS study, ENS to BiL or BiS was performed in seven volunteers. Before ENS, the volunteer relaxed the upper extremity on a table with the elbow extended and the forearm pronated. Then ENS-induced movements of the upper extremity were examined. Movements of elbow flexion and forearm supination were induced simultaneously by ENS to BiS in all volunteer and by ENS to BiL in six volunteers. ENS to BiL of one volunteer resulted in only elbow flexion. In EMG study, averaged EMGs of BiL and BiS during a to-and-fro motion from prone to supine of the forearm with holding a load were analyzed in eight volunteers. The volunteer acted the movements with keeping the elbow joint in different angles. Although an increase and a decrease of EMG activities in BiL and BiS were observed accompanied by the degree of forearm supination, patterns of changes in quantities of EMG activities to changing elbow angles varied from individual to individual. These findings seem to indicate that each human subject has an individual use of the biceps brachii for supination movements, while the action of the muscle on the elbow joint is similar among the subjects.

Adult↗
PubMed1994

Functional electrical stimulation (FES) to the biceps brachii for controlling forearm supination in the paralyzed upper extremity.

Control of forearm supination using the functional electrical stimulation (FES) to the biceps brachii was studied in a C4 quadriplegic patient. As a result of FES to the biceps brachii, and the other elbow flexors and extensors, supination was induced in maintenance of the elbow in the maximum flexion and extension, respectively. Although a range of the movements was still small and limited, these findings indicated a possibility of FES to the biceps brachii for controlling supination in paralyzed upper extremities.

Adult↗
PubMed1994

Study on the elbow movement produced by functional electrical stimulation (FES).

Functional electrical stimulation (FES)-induced movements of the upper extremity using the electromyography (EMG)-based stimulation data, which were created on the basis of EMG analysis of elbow flexion and extension in a normal human subject, were examined. As a result of the FES to the elbow flexors and extensors in another normal subject, smooth and reproducible elbow flexion and extension were controlled. This result seems to indicate not only an advantage of EMG-based stimulation data in the FES but also a great potential of FES as a new technique for the functional anatomy of the human extremities.

Elbow Joint↗
PubMed1992

Functional electrical stimulation (FES) systems for restoration of motor function of paralyzed muscles--versatile systems and a portable system.

Multichannel functional electrical stimulation (FES) systems were developed to restore the motor functions of the paralyzed muscles, i.e. two kinds of versatile systems for laboratory use and a practical portable system were developed. The first microcomputer-based FES system was composed of an 8 bit microcomputer (PC-8801mkII) with a voice recognition board and 30 stimulation outputs, in which the voice commands were used for selecting a motion pattern, and for executing (start), (hold), (restart) and (stop) commands. In combination with the voice commands, a proportional control command detected from a head angle sensor was used for volitional control of motion. The second microcomputer-based FES system was composed of a 16 bit microcomputer (PC-9801 UV or compatible) with flexible control capabilities (e.g. respiratory sensors) for volitional control and with 64 stimulation outputs. An originally designed practical portable FES system was 89 x 145 x 31 mm in dimension and 380 g in weight. This paper describes the system configurations, the control methods of these FES systems and three examples of the clinical applications of the FES systems.

Electric Stimulation Therapy↗
PubMed1991

Functional anatomical studies of the elbow movements. I. Electromyographic (EMG) analysis.

Activities of the elbow flexors and extensors during the movement of the elbow flexion and extension were analyzed in six normal human volunteers by electromyography (EMG). In the flexors, the majority of the muscles showed EMG activities during both the flexion and extension phases, although patterns and amplitudes of EMG activities varied from individual to individual. The biceps brachii always became less active when the forearm was in pronation. In the extensors, increase of EMG activities was observed at the period of the maximum elbow extension in the majority of cases, while no EMG activity was shown throughout the movement in some cases. During the elbow movement except at the maximum extension, the triceps brachii was almost inactive and some of their three heads, in particular the long head, often showed no EMG activity. In contrast, the anconeus was usually active, sometimes showing strong EMG activity.

Adult↗
PubMed1989

Development of percutaneous intramuscular electrode for multichannel FES system.

A percutaneous intramuscular electrode was developed for controlling paralyzed extremities by FES. The electrode was made of a Teflon-coated 19 strand rope wound from ultrafine SUS 316L stainless steel wires and was helically coiled for giving high flexibility. Because of low percentages of electrode failure in the body, stable and reliable FES was achieved for a long time.

Electric Stimulation Therapy↗
PubMed1989

A multichannel FES system for the restoration of motor functions in high spinal cord injury patients: a respiration-controlled system for multijoint upper extremity.

A multichannel functional electrical stimulation (FES) system for the restoration of quadriplegic upper extremity function is described. The system is composed of a personal computer NEC PC-8801mkII, peripheral electronic circuits, CRT display and respiratory sensors for volitional control by the patient, and percutaneous electrodes. A C4 quadriplegic patient could drink canned tea by herself by using this FES system. Distinct features of the system are as follows: 1) Versatile volitional control was realized by controlling the memory allocation of the stored stimulation data by voluntary respiratory signals. 2) Sophisticated fine control of the fingers, wrists, and elbow was realized by creating the multichannel stimulation data from recorded myoelectric activities of normal subjects during movements of the upper limb.

Arm↗
PubMed1987

Functional electrical stimulation for the control of the upper extremities.

A multi-channel functional electrical stimulation (FES) system for the restoration of hand function of the quadriplegic is described. The system is composed of a personal computer NEC PC-880lmkII, peripheral electronic circuits and two kinds of sensors, i.e. an analog displacement sensor for volitional control (channel 1) and a logical sensor (high pitch sound or head switch, channel 2). Combination of the two channel signals allow three major function: 1) designation of the desired prehension pattern among cylindrical grasp, key grip and parallel extension grip; 2) selection of the operation status--'start', 'proportional control', 'hold', 'stop'--and, 3) volitional control which can be controlled by the shoulder movement. In the clinical application, Caldwell-Reswick type multistrand stainless steel percutaneous electrodes were used. In this FES system, standard multi-channel stimulation patterns were obtained from electromyographical analysis of joint movement of the upper extremities in normal subjects which gave us precise information about a role of each muscle during various kinds of motion. Such stimulation patterns have enabled us to restore motor function of the paralyzed upper extremities for activities of daily living (ADL).

Electric Stimulation↗
PubMed1986

Ensemble noise and current relaxation analysis of K+ current in single isolated salivary acinar cells from rat.

The K+ channel in rat parotid gland acinar cells were investigated by ensemble current noise analysis in single isolated cells employing the giga-seal whole cell current recording mode. Sets of 20-40 identical de- and hyperpolarization voltage steps were applied and the resultant current records were processed by computer to obtain the mean and the variance of the current. The time-course of the mean current could be fitted by the sum of two exponentials, suggesting a 3-state model. The simplest plausible hypothesis is a model with one open and two closed states. Assuming this model, the relationship between the variance (sigma 2) and the mean current (I) could be fitted by the function sigma 2/I = i--I/N. The estimated single channel i/V-relations were similar to those taken from single channel current recordings, and the size of the population of channels per cell (N) was 76 +/- 26 (n = 12). The validity of the model was tested by a successful simulation of the time-course of the variance.

Animals↗