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Biomedical subjects

N I Kuznetsova

Publications and source records attributed to N I Kuznetsova.

At least 19 recordsLinked to original sources

[Changes of the immune status of children with relapsing herpetic stomatitis, suffering from allergic diseases, during licopide treatment].

The efficiency of licopide in combination with traditional treatment was evaluated in 59 children aged 1-14 years suffering from allergic diseases and relapsing herpetic stomatitis. Immunological studies were carried out before and after a course of therapy: local oral immunity, cellular immunity (in the blast transformation test with phytohemagglutinin), lymphocyte populations and subpopulations, humoral immunity values (IgA, IgM, IgG, and IgE), and C3 complement component were evaluated. The results indicate that licopide in complex with traditional methods normalized the immunological values, had a favorable impact on the course of relapsing herpetic stomatitis, and led to a stable remission of allergic diseases (p<0.001).

Acetylmuramyl-Alanyl-Isoglutamine↗

Relationship between ventricular arrhythmias and left ventricular false tendons in acute myocardial infarction.

To evaluate the association between left ventricular false tendon (LVFT) and ventricular arrhythmias in acute myocardial infarction (MI) on the 1-st day of acute MI 71 patients were examined by 24-hour ECG-monitoring and M-mode, two-dimensional, Doppler echocardiography. LVFT was detected in 30 patients (42.3%). The frequency of left ventricular fibrillation, the number of patients with multiform ectopic ventricular beats (EVB), the number of single and pair EVB and runs of ventricular tachycardia were greater in group of patients with LVFT. 37 patients had Lown grades 1-2 (A) of arrhythmias, 34 patients had grades 3-5 (B). LVFT was revealed in four patients in group A (10.8%) and in 27 patients in group B (76.5%, p < 0.001). There were no significant differences between groups in left ventricular asynergy area and wall motion score, left and right ventricular, left atrium dimensions, left ventricular contractility indices, left ventricular walls thickness, frequency of mitral regurgitation. Multifactor analysis has shown significant relationship between Lown's class value and LVFT (p < 0.0001), Lown's class and arterial hypertension (p = 0.0376). Other 17 clinical factors were not connected with Lown's class value. Thus, LVFT was associated with severe ventricular arrhythmias in patients with AMI. This fact can be used as a predictor of these disturbances.

Arrhythmias, Cardiac↗

[Cytoplasmic fractions of liver differing in their antigenic properties and alcohol dehydrogenase activity].

Organ-specific antigenous properties and alcohol dehydrogenase activity (ADH) of human and rat cytoplasmic liver fractions precipitated and not precipitated by rivanol were compared. These fractions were shown to differ in organ-specific antigenous properties, with ADH activity being largely detectable in the non-precipitated fraction. A study was also made of the action of heating (45--60 degrees C), ether and chloroform on the non-precipitated fraction to show that all these factors exert an inconsistent effect on ADH activity and organ-specific antigenous properties of the fraction. It is suggested that proteins responsible for organ-specific antigenous properties and ADH activity of the non-precipitated fraction are not identical.

Alcohol Oxidoreductases↗