Biomedical subjects
Publications and source records attributed to N Ivanov.
Two cases are reported of malignant insuloma: in one of the patients the tumor was hormonally active in the other inactive. Treatment was operative. The great difficulties in establishing the diagnosis preoperatively and the complications accompanying this grave disease are pointed out. The clinical and laboratory examinations which may help to reach at the correct diagnosis are discussed.
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In an experiment with chickens breed differences were established in accumulation of 14C-lysine, methionine and glycine, as well as intra-line differences in glycine accumulation in intestinal epitheliocytes from Plymouth Rock chickens. Differences were found in both methionine and glycine accumulation, between B line and four-line hybrids as well. Methionine accumulation in epitheliocytes from the small intestine of male chickens was higher than in female chickens from A line, higher than accumulation of tryptophane in both A and C lines and accumulation of glucose in D line. In male chickens of four-line hybrid, glycine accumulation was higher than in females.
Morphologic studies were carried out on the liver, kidneys, and small intestine of broiler birds that had been given antibiotics with the feed (virginiamycin, 20.0 ppm, flavomycin, 4.8 ppm, and avotan, 10.0 ppm) in the course of 49 days, kept with a group of controls. The liver of the test birds showed protein and fatty dystrophy, and the kidneys--protein dystrophy. The small intestine showed thinning of the wall and increase in the villi intestinales length. The manifestation of the morphologic changes depended on the amount of the antibiotic taken in. Those of the birds that were offered flavomycin had well manifested lesions, while in birds that were given virginiamycin and avotan only the lesions were more slightly expressed.
Studied was the distribution of potassium, sodium, and calcium in ram semen stored at various temperatures: 25 degrees C, 4 degrees C, and -196 degrees C. In fresh semen the concentration of K in spermatozoa and seminal plasma was 259.5 +/- 14.5 mg% and 56.4 +/- 2.1 mg%, respectively; of Na it was 38.6 +/- 3.1 mg% and 175.9 +/- 7.3 mg%; and of Ca it was 56.2 +/- 4.3 mg% and 28.0 +/- 1.9 mg%. It was found that the content of K and Ca in the spermatozoa was higher than in the plasma, while with Na the concentration in the plasma was higher than in the spermatozoa. Cooling and deep freezing of ram semen led to the redistribution of ions between spermatozoa and its natural medium, consisting in the increase in the intracellular concentration of Na and in the decrease in that of K and Ca, whereas the extracellular concentration of Na decreased and that of K and Ca increased. At all temperature values tested the concentration of K in the sperm cell was 260, 194, and 141 mg%, and that in the medium was 20.7, 21.4, and 25.6 mg%; with Na these values were 35.4, 42.3, and 49.1 mg% and 65.3, 59.1, and 45.9 mg%, and with Ca -48.0, 26.8, and 24.7 mg%, and 9.3, 9.8, and 10.8 mg%, respectively. Deep freezing was found to impair ion transport; it made it impossible for the sperm cell to restore the ion equilibrium due to irreversible changes in the structure and function of the plasmal membrane of spermatozoa.
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