N J Sheehan — Page 2 | PubMed Health

PubMed1983

Grip strength and torquometry in the assessment of hand function in patients with rheumatoid arthritis.

Hand function was studied in 33 patients with rheumatoid arthritis. Grip strength and torquometry, two distinct quantitative indices of grip, each correlated well (p less than 0.001) with the score obtained in an occupational therapy assessment of hand function both in the presence of active synovitis and chronic joint deformity. Grip strength correlated better with certain hand skills and torquometry with others, the relative relationships often being predictable from the type of grip entailed.

Adult↗

PubMed1983

Increased serum alkaline phosphatase activity in ankylosing spondylitis.

Raised serum alkaline phosphatase (AP) levels were found in 13 of 76 patients (17%) with ankylosing spondylitis (AS), and 11 of these 13 underwent further investigation to determine the origin of the increased enzyme activity. Three had levels within the normal reference range on re-estimation, and, of the remaining 8, AP isoenzyme studies indicated an increased liver fraction in 6. Serum gamma-glutamyl transpeptidase (GGT) was raised in only 3 patients. Increased AP activity did not appear to be directly related to disease activity or to drug therapy. These findings confirm the occurrence of increased serum AP activity in AS but challenge a previously reported suggestion that bone is the source of the increased enzyme.

Adolescent↗