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Biomedical subjects

N Jörgensen

Publications and source records attributed to N Jörgensen.

5 recordsLinked to original sources
PubMed1999

Exercise-induced respiratory symptoms are not always asthma.

Eighty-eight patients with a history of exercise-induced respiratory symptoms performed a maximal exercise test in order to study the reasons for stopping the test. There was a wide range of percentage maximal fall in peak expiratory flow (PEF), from minus 3% to 63%, mean 11%, recorded 0-30 min, mean 12 min after the break. In the controls the maximal decrease was 0-16%, mean 6%. Diagnostic criteria for asthma were fulfilled by 48 patients (55%). Of these patients 42% had a fall in PEF > or = 15% (exercise-induced asthma). Of the non-asthma patients 10% had a fall > or = 15%. The most common reason for stopping the exercise in the asthma group was breathing troubles (46%), the most common reason in the non-asthma group was chest pain/discomfort (35%). In about 20% of the patients dizziness and/or pricking sensations in arms or legs indicated hyperventilation as an additional reason for stopping the exercise. It is concluded that other kinds of reaction, than bronchial obstruction such as breathing troubles not directly related to bronchial obstruction and chest pain, may be important factors that can restrict physical capacity in patients with exercise-induced respiratory symptoms.

Adolescent↗
PubMed1997

[Asthma or asthma-like condition?].

Asthma is currently seen as an inflammatory disease of the airways. The clinical characteristics are any of a variety of airway symptoms occurring in conjunction with bronchial obstruction (which is reversible on treatment with beta 2-agonists or steroids) and bronchial hyper-responsiveness. The symptoms can be triggered by a variety of factors and the clinical picture is not uniform. The most common differential diagnoses are chronic obstructive lung disease (COLD) and asthma-like conditions unaccompanied by bronchial obstruction.

Adult↗
PubMed1996

[Severe asthma was found to be an asthma-like condition. Consider reduced doses of cortisone].

A middle-aged man with variable breathing problems and frequent acute attacks, diagnosed as severe bronchial asthma, was given high-dose oral corticosteroid treatment. Owing to the somewhat atypical history, and normal lung function test results despite severe concomitant asthma-like symptoms, the diagnosis was reconsidered. As a new diagnostic work-up showed the presence of a disease of slight to moderate severity, it was decided to taper off the corticosteroid treatment. Within one year the daily dose of prednisolone was decreased from 40 to 7.5 mg without deterioration of the airway symptoms or impairment of lung function. Re-evaluation also showed the principal diagnosis not to be bronchial asthma but an asthma-like condition (functional breathing disorder combined with sensory hyperresponsiveness), and alternative not previously considered and a condition in which steroids are without apparent effect. This case illustrates the importance of a critical re-view of the diagnosis before high-dose corticosteroid treatment with its inevitable side effects is instituted.

Acute Disease↗
PubMed1993

Fatal cadmium-induced pneumonitis.

A previously relatively healthy 78-year-old man was exposed to cadmium fumes during brazing with cadmium-containing silver solder. He developed severe chemical pneumonitis and died 25 d after exposure.

Aged↗