Biomedical subjects

N Janakiramiah

Publications and source records attributed to N Janakiramiah.

3 recordsLinked to original sources

PubMed1998

Acute post-ECT cardiovascular response: a comparison of threshold right unilateral and bilateral ECT.

The effect of electrode placement on cardiovascular responses was studied. Rate pressure product and diastolic blood pressure before anesthesia and 30 s after electroconvulsive therapy (ECT) seizure were recorded. Recordings were made at the first (threshold ECT) session in 124 bilateral ECT (BLECT) and 95 unilateral ECT (ULECT) consenting patients. Postictal rate pressure product (RPP) was significantly higher after BLECT than ULECT. Mean increase in RPP from pre- to postictal phase was 31% in the former. The corresponding change with ULECT (20%) was significantly smaller. In the stepwise, multiple regression model, pre-ECT RPP, age, and stimulus laterality significantly contributed to postictal RPP. No cardiovascular complications occurred in any of the 219 ECT sessions.

Adult↗

PubMed1998

Formula method for stimulus setting in bilateral electroconvulsive therapy: relevance of age.

Seizure thresholds were determined by titration in consecutive electroconvulsive therapy (ECT) patients at the first (n = 146) and sixth (N = 83) ECT sessions. Equations to predict the threshold at the first and sixth ECT were computed from these data using a stepwise linear regression model. These equations were tested prospectively at the first ECT (n = 48) and sixth ECT (n = 26) sessions. Stimulus dose derived from the corresponding equations yielded adequate seizure (successful) in 82% and 84% of patients, respectively. Predictions based on age alone (disregarding two other significant variables--illness severity and inion-nasion distance) were estimated at these two ECT sessions. This would not appreciably compromise the success rate. The "formula" method using age alone may therefore be used in routine clinical practice.

Adolescent↗

PubMedDate not supplied

Lycanthropy in depression: two case reports.

Two cases of lycanthropy presenting as part of a depressive disorder are described. The patients responded favorably to pharmacotherapy. In both cases, a positive history of dog bite influenced the presentation of symptoms. The authors speculate whether the defense of identification with the aggressor was operative.

Adolescent↗