Biomedical subjects

N Jeremy Kasdin

Publications and source records attributed to N Jeremy Kasdin.

5 recordsLinked to original sources

PubMed2007

Going wild: what a global small-animal tracking system could do for experimental biologists.

Tracking animals over large temporal and spatial scales has revealed invaluable and spectacular biological information, particularly when the paths and fates of individuals can be monitored on a global scale. However, only large animals (greater than approximately 300 g) currently can be followed globally because of power and size constraints on the tracking devices. And yet the vast majority of animals is small. Tracking small animals is important because they are often part of evolutionary and ecological experiments, they provide important ecosystem services and they are of conservation concern or pose harm to human health. Here, we propose a small-animal satellite tracking system that would enable the global monitoring of animals down to the size of the smallest birds, mammals (bats), marine life and eventually large insects. To create the scientific framework necessary for such a global project, we formed the ICARUS initiative (www.IcarusInitiative.org), the International Cooperation for Animal Research Using Space. ICARUS also highlights how small-animal tracking could address some of the ;Grand Challenges in Environmental Sciences' identified by the US National Academy of Sciences, such as the spread of infectious diseases or the relationship between biological diversity and ecosystem functioning. Small-animal tracking would allow the quantitative assessment of dispersal and migration in natural populations and thus help solve enigmas regarding population dynamics, extinctions and invasions. Experimental biologists may find a global small-animal tracking system helpful in testing, validating and expanding laboratory-derived discoveries in wild, natural populations. We suggest that the relatively modest investment into a global small-animal tracking system will pay off by providing unprecedented insights into both basic and applied nature. Tracking small animals over large spatial and temporal scales could prove to be one of the most powerful techniques of the early 21st century, offering potential solutions to a wide range of biological and societal questions that date back two millennia to the Greek philosopher Aristotle's enigma about songbird migration. Several of the more recent Grand Challenges in Environmental Sciences, such as the regulation and functional consequences of biological diversity or the surveillance of the population ecology of zoonotic hosts, pathogens or vectors, could also be addressed by a global small-animal tracking system. Our discussion is intended to contribute to an emerging groundswell of scientific support to make such a new technological system happen.

Animal Migration↗

PubMed2006

On representing and correcting wavefront errors in high-contrast imaging systems.

Conventional adaptive-optics systems correct the wavefront by adjusting a deformable mirror (DM) based on measurements of the phase aberration taken in a pupil plane. The ability of this technique, known as phase conjugation, to correct aberrations is normally limited by the maximum spatial frequency of the DM. In this paper we show that conventional phase conjugation is not able to achieve the dark nulls needed for high-contrast imaging. Linear combinations of high frequencies in the aberration at the pupil plane "fold" and appear as low-frequency aberrations at the image plane. After describing the frequency-folding phenomenon, we present an alternative optimized solution for the shape of the deformable mirror based on the Fourier decomposition of the effective phase and amplitude aberrations.

Journal Article↗

PubMed2005

Optimal one-dimensional apodizations and shaped pupils for planet finding coronagraphy.

The realization that direct imaging of extrasolar planets could be technologically feasible within the next decade or so has inspired a great deal of recent research into high-contrast imaging. We have contributed several design ideas, all of which can be described as shaped pupil coronagraphs. We offer a complete and unified survey of one-dimensional shaped pupil designs, some of which have been published in our previous papers. We also introduce a promising new design, which we call bar-code masks. With these masks we can achieve the required contrast with a fairly large discovery zone and throughput, but most importantly they are perhaps the easiest to manufacture and might therefore stand up best to refined analyses.

Journal Article↗

PubMed2005

Hamilton-Jacobi modelling of relative motion for formation flying.

A precise analytic model for the relative motion of a group of satellites in slightly elliptic orbits is introduced. With this aim, we describe the relative motion of an object relative to a circular or slightly elliptic reference orbit in the rotating Hill frame via a low-order Hamiltonian, and solve the Hamilton-Jacobi equation. This results in a first-order solution to the relative motion identical to the Clohessy-Wiltshire approach; here, however, rather than using initial conditions as our constants of the motion, we utilize the canonical momenta and coordinates. This allows us to treat perturbations in an identical manner, as in the classical Delaunay formulation of the two-body problem. A precise analytical model for the base orbit is chosen with the included effect of zonal harmonics (J(2), J(3), J(4)). A Hamiltonian describing the real relative motion is formed and by differing this from the nominal Hamiltonian, the perturbing Hamiltonian is obtained. Using the Hamilton equations, the variational equations for the new constants are found. In a manner analogous to the center manifold reduction procedure, the non-periodic part of the motion is canceled through a magnitude analysis leading to simple boundedness conditions that cancel the drift terms due to the higher order perturbations. Using this condition, the variational equations are integrated to give periodic solutions that closely approximate the results from numerical integration (1 mm/per orbit for higher order and eccentricity perturbations and 30 cm/per orbit for zonal perturbations). This procedure provides a compact and insightful analytic description of the resulting relative motion.

Journal Article↗

PubMed2004

Hamiltonian modelling of relative motion.

This paper presents a Hamiltonian approach to modelling relative spacecraft motion based on derivation of canonical coordinates for the relative state-space dynamics. The Hamiltonian formulation facilitates the modelling of high-order terms and orbital perturbations while allowing us to obtain closed-form solutions to the relative motion problem. First, the Hamiltonian is partitioned into a linear term and a high-order term. The Hamilton-Jacobi equations are solved for the linear part by separation, and new constants for the relative motions are obtained, they are called epicyclic elements. The influence of higher order terms and perturbations, such as the oblateness of the Earth, are incorporated into the analysis by a variation of parameters procedure. Closed-form solutions for J(2-) and J(4-)invariant orbits and for periodic high-order unperturbed relative motion, in terms of the relative motion elements only, are obtained.

Journal Article↗