Biomedical subjects
Publications and source records attributed to N Jiang.
Ultrafiltration is an important step in isolation and purification of pullulan. Here a new formula for ultrafilter calculation is derived from experiments about the relationship between the ultrafiltrate rate and the concentration of pullulan solution. It can be used for calculating and designing of ultrafilter under defined production scale and its related technical parameters.
The cell of origin and giant cell tumor remains unknown, but on the basis of most experimental evidence it is probably a mesenchymal cell showing some macrophage characteristics. The clinical features which have led people to suggest that this tumor may be a steroid receptor positive lesion are tenuous at best. Early histochemical data suggesting a presence of estrogen and progesterone receptors in giant cell tumor have not been substantiated by further studies. Immunohistochemical techniques have not identified estrogen receptors in giant cell tumor. Multiple biochemical techniques have failed to identify clinically significant levels of estrogen or progesterone receptors in giant cell tumor.
Ketosteroids, the excretory metabolities of adrenal and gonadal steroids, can be analyzed individually in urine by a simple extraction procedure followed by separation and quantitation by the use of gas/liquid chromatography. The ketosteroids quantitatively detected by the technique are androsterone, etiocholanolone, dehydroepiandrosterone, 11-hydroxyandrosterone, 11-hydroxyetiocholanolone, 11-ketandrosterone, and 11-ketoetiocholanolone. Other steroid metabolities detected are pregnanediol, pregnanetriol, delta5-pregnenetriol, and 11-ketopregnanetriol. In comparison with concentrations of these steroids observed in urine specimens collected from healthy individuals, abnormal results occur in specimens from patients with testicular disease, Cushing's syndrome, adrenal hyperplasia, and several types of female hirsutism. Characteristic profiles for each of these diseases are presented.