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N Jindal

Publications and source records attributed to N Jindal.

26 records · Page 2Linked to original sources
PubMed1994

Presumptive identification & antibiotic susceptibility of group B Streptococci.

Three presumptive identification tests were conducted on 60 strains of beta haemolytic group B streptococci (GBS) & evaluated for their sensitivity as compared to the standard serological grouping. The GBS were further subjected to serotyping and antibiotic sensitivity testing. Hippurate was hydrolysed by 96.6%, the CAMP test was positive in 83.3% & pigment was produced by 95%. The commonest serotype was la (33.3%) followed by lb (30%). Hundred percent strains were sensitive to Penicillin, Ampicillin, Erythromycin & Cephlexin. 76.7% showed MIC of 50 ug/ml or more for Tetracycline & 66.7% were inhibited by 3.2 ug/ml or less of Gentamicin.

Anti-Bacterial Agents↗
PubMed1992

Diagnostic accuracy of IgM antibody detection in typhoid by a modification in Widal test.

Specific IgM antibodies were detected indirectly in sera of patients of typhoid by observing fourfold or more fall in the agglutinin titres after treatment of the serum with 2-mercaptoethanol (2-ME) for removal of IgM antibodies. Significant fall in titres was observed in 94 per cent patients of bacteriologically confirmed typhoid and 67 per cent patients in whom a diagnosis of typhoid was based only on a significant Widal test result. Patients of non-typhoid febrile illnesses showed either no fall or an insignificant fall in their titres. The detection of specific IgM antibodies by this simple modification of Widal test thus seems to enhance the sensitivity and specificity of the test.

Agglutination Tests↗
PubMed1991

Role of faecal leucocytes in the diagnostic evaluation of acute diarrhoea.

The value of faecal leucocyte examination was assessed in 400 infants with acute diarrhoea and 40 normal healthy infants. Enteropathogens were isolated from 28.75%. Escherichia coli was the commonest (16.5%) followed by Salmonella typhimurium (7%), Vibrio cholerae (3.25%) and Shigella flexneri (1.5%). Exudative response was observed in 57.1% of stools with Salmonella and 66.6% each with Shigella and E.I.E.C. infections. 81.3%, 89.5% and 87.7% of stools from which EPEC and ETEC and no enteropathogens respectively were isolated showed minimal or no Leucocytic response. The test is useful to recognise probable invasive bacterial diarrhoea and to decide the cases in which stool culture could be advantageous.

Diagnosis, Differential↗
PubMed1990

Anaerobic bacterial flora of wound sepsis.

Two hundred specimens from wound infection (surgical and non-surgical) were cultured for the isolation of anaerobic and aerobic bacteria. Positive cultures were obtained in 174 (87%) and 26(13%) were sterile. Anaerobes were isolated from 31(17.8%), as single culture in 6(3.4%) and as mixed culture with aerobes in 25(14.3%). Amongst anaerobes, anaerobic cocci were predominant (45.9%). Of aerobes Staph pyogenes (35%) was predominant. Metronidazole was the most effective drug against anaerobes and gentamicin against aerobes. No significant difference was noted in antimicrobial susceptibility of anaerobes of surgical and non-surgical wounds. Among aerobes high resistance was observed in surgical wounds.

Bacteria, Aerobic↗
PubMedDate not supplied

Effect of ochratoxin A on Escherichia coli-challenged broiler chicks.

A study was conducted to evaluate the effects of ochratoxin A (OA) on Escherichia coli-challenged broiler chickens. Day-old broiler chicks were separated into two groups of 92 chicks each, with one group fed a control mash diet, and the other fed a mash diet containing 2 ppm OA. On day 14, each group was further separated into two groups, with one group inoculated with E. coli O78 (1 x 10(7) colony-forming units/0.5 ml), whereas the other group was not inoculated with E. coli. After E. coli inoculation on day 14, four birds from each group were euthanatized at 1, 2, 3, 5, 7, 10, 14, and 21 days postinoculation. Escherichia coli infection caused dullness, depression, huddling, and diarrhea. Mortality was 14.3% in chicks infected with E. coli but fed no OA. Mortality increased to 35.7% in chicks fed OA and infected with E. coli. Decreased body weight and reduced feed intake were observed in chicks fed OA, and the effects were more pronounced in chicks fed OA and infected with E. coli. Increased serum levels of aspartate aminotransferase, alanine aminotransferase, uric acid, and creatinine and decreased levels of total proteins, albumin, globulins, calcium, and phosphorus were observed in OA-fed birds. Escherichia coli infection did not cause significant alteration in any of the serum biochemical parameters. The presence of OA in poultry rations increased mortality and the severity of an E. coli infection.

Animal Feed↗
PubMedDate not supplied

Ultrastructural and histological study of endomyocardial biopsies from patients of dilated cardiomyopathy--a comparative evaluation and their clinical correlation.

Morphological studies of dilated cardiomyopathy reveal nonspecific light and electron microscopic features. This study was designed to perform a comprehensive qualitative and semi-quantitative evaluation of histological and ultrastructural parameters in endomyocardial biopsies in 20 cases of DCM. Semi-quantitation of parameters increases the accuracy and precision of evaluation by reducing interobserver variation in assessment. The semi-quantitative score ratios in our study were further correlated with the clinical and hemodynamic data to identify parameter(s) of prognostic significance. In the histological evaluation, myofibre hypertrophy appeared to be the most frequent (95%) and severely affected parameter followed by myocardial degeneration (70%). The ultrastructural features were more diffuse, impressive and severely altered. The most prominent features were mitochondrial degeneration and myofibrillar lysis seen in 100% of our cases. Severe mitochondrial degeneration appeared to be an indicator of poor prognosis in DCM as it was seen in patients with the lowest left ventricular ejection fraction obtained angiographically. Moreover, unlike the light microscopic evaluation, ultrastructural score ratios correlated significantly with the ejection fraction.

Adult↗