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N Juznić

Publications and source records attributed to N Juznić.

11 recordsLinked to original sources
PubMed1991

Alpha 2 macroglobulin in healthy pregnant women and those with EPH gestosis.

The Authors determined alpha 2 macroglobulin in 50 healthy pregnant women and in 50 pregnant women with EPH gestosis, using the technique of nephelometry on the Immunochemistry Analyzer. The assays were done in blood serum of the mother and umbilical cord, urine and in the amniotic fluid of the affected patients. Serum values were expressed in gr/L, and amniotic fluid and urine values in mg/L. Significant reduction was found in the pregnant women with EPH gestosis in serum values of the mothers (healthy pregnant women 2.871 g/L +/- 1.015, with EPH gestosis 2.239 g/L +/- 1.323, p less than 0.05), and in the umbilical cord serum (healthy pregnant women 3.351 g/L +/- 0.859, affected ones 2.032 g/L +/- 0.693 g/L, p less than 0.01). The reduction was also noted in the urine values but was significant one. The importance of these determinations is presented in the discussion.

Amniotic Fluid↗
PubMed1991

[Levels of immunoglobulins in various media from healthy pregnant women and women with diabetes mellitus and EPH gestosis].

The introduction deals with of the history, etiology and, briefly, clinical manifestations of endemic nephropathy. The authors state that a large number of investigations have been done until today, but without producing a diagnostic test for early diagnosis of the disease. This led the authors to pursue certain laboratory investigations. The control group consisted of 30 healthy individuals while patients diagnosed as Endemic Nephropathy were grouped according to stages of the disease: initial, developed, terminal stages. Nucleotides in erythrocytes (5' UMP, 5' IMP, 5' GMP, 5,CMP, 5' AMP, 5' ADP, 5' ATP) were determined on the Acidic Aminoanalyzer, with use of a special UV detector. Catecholamines in the urine were determined by using ratiofluorometery. Creatinine phosphocinase, hydroxybutirat--dehydrogenase and 2,3 DPG were determined on the "Carlbiochem" enzymometer. LDH, its isoenzymes as well as its profile were determined by electrophoresis on starch gel. Specific proteins such as haptoglobin, alpha 2 macroglobulin, alpha 1 antitrypsin, alpha 1 acid glycoprotein, properdin factor B, ceruloplasmin were determined on the Immunochemistry Analyzer. Total cholesterol and cholesterol in lipoproteins fractions VLDL, LDL and HDL were determined on the Cholesterol Analyzer. All results were evaluated statistically. Our conclusion is that they are interesting and contribute to the diagnosis of endemic nephropathy.

Adult↗
PubMed1990

The complements and immunoglobulins in different media of healthy pregnant women and in pregnant women with increased blood pressure.

We have determined the levels of complement C3, C4 and immunoglobulin G, M, A in mothers' and cord blood serum. Parallelly properdin factor B and immunoglobulin G tests were done in urine samples. All estimations were performed on Immunochemistry Analyzer "Beckman". The investigations were made on 30 healthy pregnant women and 30 with arterial hypertension at the end of third trimester. In the mothers' serum C3 was not significantly changed. In the cord blood of healthy pregnant women it was 0.69 g/L. (SD 0.12) and in those with hypertension 0.38 g/L. (SD 0.15), which means significantly decreased. Complements C4 was not significantly increased in mothers' and cord blood serum. Properdin factor B was significantly increased in mothers' and cord blood serum (healthy pregnant women in serum 0.38 g/L., SD 0.07; with hypertension 0.48 g/L., SD 0.15; while in the cord blood serum of healthy women it was 0.14 g/L., SD 0.06; and hypertensive it was 0.22 g/L., SD 0.10). The same parameter was significantly decreased in the urine of healthy subjects 3.94 mg/L., SD 1.91; and in the hypertensive too, 2.42 mg/L., SD 0.90. The IgG level was significantly increased in the urine of healthy pregnant women 4.42 mg/L., SD 2.24; with hypertension 6.64 mg/L., SD 3.61. IgM was not significantly changed in mothers' and cord blood serum. IgA was significantly increased in the cord blood serum of healthy mothers', 0.02 g/L., SD 0.01, with hypertension 0.12 g/L., SD 0.05.

Complement C3↗
PubMed1988

The significant of complement and immunoglobulin determination in healthy pregnant women and patients with EPH gestoses.

Complements C3 and C4, IgG, IgM, IgA and properdin factor B (PFB) were determined in maternal blood sera, sera from the umbilical cord and amniotic fluid in the group consisting of 30 healthy pregnant women and 30 patients with EPH gestoses. PFB and IgG were measured in urine, as well. Significant decrease of C3 complement in maternal sera and PFB in urine was found in the group with EPH gestoses, while a slight C4 complement enhancement was recorded in both maternal sera and the blood sera from the umbilical cord. PFB was conspicuously increased in maternal blood sera. IgG level was higher in the blood sera from the umbilical cord in comparison with that found in maternal sera in both groups examined. IgG, IgM and IgA levels were decreased in the group of patients with EPH gestoses in all fluids examined, while IgA level was significantly increased in the sera prepared from the blood from the umbilical cord.

Amniotic Fluid↗
PubMedDate not supplied

[Treatment of ectopic pregnancy using methotrexate].

The authors applied the conservative treatment of ectopic pregnancy with methotrexate in a prospective study comprising 22 patients. Out of this number, 14 patients had intact ectopic pregnancy and 8 showed the signs of initial tubal abortion (as proved by the hematocele finding). This group of 8 patients insisted to be given the same therapy, although they were informed of the possible failure in cases of initial tubal abortion. In all these cases methotrexate was administered locally, injected into the gestational sac under ultrasonic monitoring. In addition to the local application, 13 patients systemically received the same drug in pills (2.5 mg). At the same time, all the patients were given the antidote (Citrovorum factor). This method of treatment appeared to be successful in 16 patients (72.7%), four of them also having hematocele. Surgical treatment was applied afterwards in six patients (27.3%).

Female↗
PubMedDate not supplied

[Complement and immunoglobulin levels in pregnant women with EPH gestosis].

The authors determined C3 and C4 complements, factor B properdin and immunoglobulins G, M and A in 20 healthy pregnant patients and in 20 patients with EPH gestosis. The analysis was performed in mothers sera, umbilical sera and amniotic fluid, and properdin factor B and IgG in urine. They used the nonfellometric technique with immunochemistry analyzer. The C3 complement was very increased in the serum of mothers with EPH gestosis, and complement C4 was slightly increased in the serum of EPH gestosis, and complement C4 was slightly in the serum of EPH gestosis, and complement C4 was slightly increased in the serum of mothers and umbilical sera. Factor B properdin was very increased in mothers sera and decreased in urine. Higher concentrations of immunoglobulin G were found in umbilical sera than in mothers sera. Increased concentrations of sera in mothers, the umbilicus and urine were observed in patients with EPH gestosis. In these patients IgM was decreased in the serum of mothers and the umbilicus. IgM was decreased in the serum of mothers and significantly increased in umbilical sera. Significant changes in patients with EPH gestosis were noted.

Complement Factor B↗
PubMedDate not supplied

[Cervicography--a useful method for the early detection of changes in the uterine cervix].

Cervicographic findings were analysed in 156 patients of whom 71 had previously been found to have cervical changes (group I) and 85 were regularly examined within the periodic systematic examination programme (group II). In group I there were 15.5% negative cervicographic findings, 80.3% suspect, and 4.2% technically inadequate. Out of suspect findings, carcinoma in situ or invasive carcinoma were detected in 54.4%, of which 9.7% were cytologically false negative. In group II, in 69.4% of cases, some colposcopic changes (non-malignant) were observed, while in 3 out of 26 colposcopically normal findings, there were some changes in the cervicogram.

Colposcopes↗
PubMedDate not supplied

[A case report of collision in twin pregnancy].

A parturient who had never been examined during pregnancy was admitted to the maternity ward at the end of the first phase of labour. Owing to a stoppage in the expulsion of the regularly rotated head, the forceps was applied. The extraction of the head was followed by the collision of the shoulders. Behind the fetus's neck, in the uterine canal, there was the head of the other fetus. The attempt of the reposition of the head of the other twin in general anesthesia was a failure. Since auscultation revealed no heart tones in any of the twins, the perforation of the head of the other fetus was performed, and in this way the extraction of the first and then of the second fetus was possible. The authors emphasize the importance of the echographic detection of the position and site of the fetuses in twin pregnancy.

Adolescent↗
PubMedDate not supplied

[Cervical clefts as a possible etiologic factor in sterility].

Follow-up gynecological and colposcopic examinations performed in 81 patients after the puerperium have shown that out of 15 sutured ruptures only 9 (60%) healed. The follow-up colposcopic examination revealed 19 unstitched clefts of which 13 did not heal and 6 healed leaving a scar (31.5%). The ectopy of the cervical mucosa was found 5 times (33.3) in the group of stitched clefts and 8 times (47.3%) in the group of unstitched clefts, among which there was also leukoplakia in one case. In the group without the injury of the cervix, ectopia was observed in 11 cases (23.4%). In the course of 1979, at the Gynecology Department, cerclage was performed 474 times. Out of these cases, 20 women (4.2%) underwent cerclage owing to the cleft of the uterine cervix and previous spontaneous abortions. The authors recommend a careful surgical treatment of the cleft and consider the revision of the cervix after each delivery absolutely necessary, both these measures being meant to serve as prevention against sterility and infertility.

Cervix Uteri↗