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Biomedical subjects

N K Agrawal

Publications and source records attributed to N K Agrawal.

34 records · Page 2Linked to original sources

Neurological manifestations associated with bronchogenic carcinoma.

Neurological manifestations of bronchogenic carcinoma were studied in 50 cases, 42% of whom showed neurological abnormalities with 6% having more than one type. Recurrent laryngeal nerve paralysis (20%) was the commonest, phrenic nerve paralysis (2%), paraneoplastic syndrome (12%), Pancoast's syndrome (10%) and metastatic involvement of central nervous system (4%) were other neurological manifestations. No evidence of encephalitis, motor neurone disease, myelopathy, Eaton-Lambert syndrome, myositis and drug-induced peripheral neuropathy was found in this study.

Brain Neoplasms↗

A study of the adjustment of patients in relation to their prosthodontic problems.

Patients' self-concept and personality have been shown to deteriorate with an increase in prosthodontic problems. This study determined whether patients with prosthodontic problems varying in severity showed different levels of adjustment. Four groups of patients, including a control group, were studied. The three experimental groups differed from the control group and varied in their adjustment in relation to their prosthodontic problems.

Adaptation, Psychological↗

Hematological changes due to vitamin C deficiency in Channa punctatus Bloch.

Hematological changes in Channa punctatus based on examination of blood at regular monthly intervals in fishes fed a vitamin C-deficient diet for 210 days followed by 30 days' recovery treatment have been reported. Normochromic normocytic type of anemia was observed after 120 days of vitamin C deficiency which developed into a normochromic macrocytic type eventually becoming hypochromic macrocytic during the last 30 days of deficiency. Correlated erythropoietic studies revealed a decrease in small lymphoid hemoblast with simultaneous increase in the later stages of red blood cell development. Deficiency also resulted in leukocytosis, basically due to thrombocytosis. Differential leukocyte counts revealed relative decrease in all other cell types particularly neutrophils and lymphocytes. Recovery treatment was found effective in arresting and in most cases reversing the pathological trends set in by the deficiency.

Animals↗

Protective role of ascorbic acid in fishes exposed to organochlorine pollution.

Protective role of ascorbic acid on the toxic effect of aldrin pollution in an air-breathing fish Channa punctatus Bloch is reported. Fishes fed with aldrin mixed diet at 0.25% showed 25% mortality in 30 days. Mortality is preceded by certain changes in peripheral blood such as polycythemia and leucocytosis with increased thrombocyte but decreased neutrophil population. However, a massive dose of ascorbic acid (500 mg/100 g diet) was found to considerably neutralize the toxic effect as evidenced by 10-fold decrease in mortality and significantly lowered haematological response. The significance of these studies in the light of physiological role of ascorbic acid as a micronutrient for protection against pollution stress is discussed.

Aldrin↗