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Biomedical subjects

N K Bhide

Publications and source records attributed to N K Bhide.

At least 19 recordsLinked to original sources
PubMed1991

DDT levels in human body fat & milk samples from Delhi.

A study of 45 human fat samples from autopsy and surgery specimens from Delhi showed a mean total DDT level of 6.37 micrograms/g (SE +/- 0.36; range 3.34-9.12 micrograms/g). While these values compare well with those reported from India and abroad, they are much lower than those obtained from other areas of Delhi, confirming wide variation in the quantity of DDT sprayed in different pockets of this city. Twenty one human milk samples from Delhi showed a mean total DDT level of 0.144 ppm (micrograms/ml). Thus, many infants in Delhi appear to be consuming 3 to 5 times the permissible 5 micrograms/kg/day quantity of DDT. This study too indicates the need of continuous monitoring of DDT and other insecticides commonly used in India.

Adipose Tissue↗
PubMed1990

Skin and liver toxicity in experimental Lantana camara poisoning in albino rats.

Dried alcoholic extract of fresh Lantana camara leaves (LE), on oral administration to albino rats of both sexes, induced photodermatitis during exposure to clear sunlight for 1 hr. Its severity was related to the dose of LE and was maximal in rats exposed to sunlight from 4 to 14 hr after feeding LE and gradually declined over 40 hr. Wavelengths of light about 540 to 570 mu only were effective. In control study, the alcoholic extract of edible spinach leaves was only 1/3 in potency and its effect lasted for less than 20 hr. LE did not raise serum bilirubin, SGOT, SGPT or cause liver injury as assessed by light microscopy. However, like CCL4 but unlike spinach extract, LE impaired excretion of BSP by liver, proportionate to the dose and also maximal at 5.5 hr declining thereafter over 40 hr.

Animals↗
PubMed1976

Intensive care in rabies therapy. Clinical observations.

Seven patients in India with dog-bite rabies were treated by intensive therapy. Hypoxia was prevented by intermittent positive-pressure ventilation facilitated by muscle relaxants and sedatives. Other measures, included maintenance of nutrition, correction of fluid/electrolyte and acid/base balances, antiviral agents, immunological stimulation, and intensive nursing care by immunised volunteer staff. The patients survived for from 1 to 17 days after the onset of clinical disease. When survival was prolonged (i.e., more than 2-4 days) by intensive care, the disease had diverse and serious effects, including fluctuations in temperature and blood-pressure, cardiac arrhythmia, and diabetes insipidus. Although none of the patients survived, advances in the use of this technique raised hopes that it may eventually be possible to save some patients.

Cytarabine↗