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Biomedical subjects

N K JERNE

Publications and source records attributed to N K JERNE.

13 recordsLinked to original sources
PubMed1956

The stability of biological standards.

The authors emphasize the importance of stability in biological standards and discuss the steps taken to ensure the stability of International Standards and the theoretical basis of the various stability tests used.

Biological Products↗
PubMed1954

The unit in preference to the titre as a measure of agglutinating activity.

The agglutinating activity of individual sera is usually expressed by a "titre" notation, the titre being dependent on the degree of agglutination arbitrarily chosen as the end-point. This titre may be corrected by comparison with a standard serum. A "unit" notation, however, necessarily requires both comparative measurements in relation to a standard serum and the taking into consideration of all degrees of agglutination. This involves log-dose-response curves for the standard serum and the test serum; and cases in which the distance between such curves is not constant, either at different degrees of agglutination or where different antigen suspensions are used, will bring to light fundamental limitations of the bio-assay which the simple use of titres may not reveal.

Humans↗