Rubella immunisation and embryopathy.
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Biomedical subjects
Publications and source records attributed to N K Kappagoda.
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A healthy 42 yr-old woman presented with a left keratitis which she had had for 3 months. No organisms could be grown by culture of corneal scrapings for bacteria and fungi, and the condition failed to respond to topical therapy. Amebic keratitis was diagnosed following corneal biopsy and cultures which grew Acanthamoeba of a species similar to, but not identical with, Acanthamoeba polyphaga. Medical treatment was continued for 6 mth. During this time the corneal infiltrate became less prominent but visual acuity remained impaired by both corneal opacity and cataract.
The sera of 30 patients with complement-fixing antibodies to Mycoplasma pneumoniae (titres larger than or equal to 32) were treated with staphylococcal protein A. This procedure effectively removed 90 to 95% of the IgG antibodies. The Mycoplasma-specific antibodies in the treated sera could then be measured by a complement fixation test. This provides a useful test for distinguishing serological responses to recent Mycoplasma pneumoniae infections from anamnestic responses due to past exposure to Mycoplasma pneumoniae.