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Biomedical subjects

N K Loginova

Publications and source records attributed to N K Loginova.

At least 19 recordsLinked to original sources

[The microcirculation in the periodontal tissues: I. The dynamics of functional hyperemia].

Study of functional hyperemia of the gingival microcirculatory network by biomicroscopy and laser Doppler flowmetry showed that in normal periodontium, the microcirculation index increased by 70% immediately after mechanical loading created by the gnathodynamometer, whereas in slight or medium-severe periodontitis it increased only by the and of the first minute, the peak bloodflow values being 31 and 19%, respectively. In grave periodontitis the microcirculation index was 6% decreased immediately after loading and increased only by the fifth minute, which is explained by notable changes in the angioarchitectonics of periodontal microvessels.

Bite Force

[The microcirculation in periodontal tissues: 2. The action of the regular use of chewing gum].

The effect of regular use of chewing gum (for 28 days) on microcirculation was assessed in 35 patients with slight and medium-severe periodontitis by biomicroscopy and laser Doppler flowmetry. Microcirculation normalized immediately after chewing training due to arrest of arteriolar spasm. In slight periodontitis the effect persists for almost one year, in medium-severe condition for up to 6 months, because of more expressed structural changes in the microvessels of periodontal tissue.

Chewing Gum

[Relation between functional-immunological and clinical parameters in juvenile periodontal diseases].

In 57 Moscow adolescents aged 15 to 19 years gingival bleeding and periodontal pocketing was recorded. In addition to this functional parameters of Rheoperiodontography and Polarography were documented and immunological investigations were carried out. The clinical parameters of the test group showed a higher level of periodontal diseases compared with a random selected control group. A correlation between clinical and functional parameters in early periodontal destruction was not detected. This study demonstrates the importance of prevention of periodontal diseases in adolescents.

Adolescent

[Role of salivary kallikrein in the pathogenesis of periodontosis].

In patients with parodontosis the distinct increase in salivary kallikrein secretion was found. In Wistar rats the intensity of age atrophy of alveoli dentalis correlated with BAEE-esterase activity of mixed saliva. Desalivation considerably decreased the rate of age atrophy of parodontosis in rats. Salivary kallikrein, penetrating in active form into parodontal tissues, caused the pronounced vasodilation in dogs and golden hamsters. By means of kallikrein preparations an intensive inflammatory-dystrophical process was reproduced in parodontal tissues of Wistar rats. The local treatment of patients with parodontosis by kallikrein inhibitors was found to be especially effective.

Acetone

[Normobaric pulsed hypoxic stimulation in the combined therapy of periodontitis in adolescents].

Hypoxic stimulation was added to local therapy of periodontitis in 26 adolescents with the initial manifestations of this condition. Analysis of the results has shown that hypoxic stimulation enhanced the body adaptive and compensatory potentialities, was conductive to recovery of the disordered oxygen metabolism and normalization of the regional hemodynamics and periodontal microcirculation.

Adaptation, Physiological

[The oxygen regimen of the periodontal tissues in adolescents].

Studies of changes in gingival oxygen tension (pO2) carried out in adolescents with initial inflammatory processes in the periodontium have revealed that pO2 reduced negligibly over the course of periodontitis development. Hypoxic test has detected essential changes in pO2 drop and recovery rates in gingival tissues, which may be a sign in the differential diagnosis of gingivitis and periodontitis.

Adolescent

[An assessment of the variations in periodontal pathology in adolescents].

Forty-seven adolescents with periodontal abnormalities were examined using clinical, immunologic, and functional tests (altogether 12 signs). Factor analysis helped cut down the number of signs just to 4 major factors. Interpretation of these factors and consideration of the individuals in factor space permitted singling out at least 2 types of periodontitis course, requiring, possibly, different approaches to therapy.

Adolescent