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Biomedical subjects

N K Nkanza

Publications and source records attributed to N K Nkanza.

13 recordsLinked to original sources

Chromosomal abnormalities: experience at Harare Hospital.

A study of 107 cases with chromosomal abnormalities seen over a four-year period is presented. The commonest abnormality was Trisomy 21 which accounted for 37% of all cases. There were also many cases with intersex. The results of this study were similar to a previous one done in the same department a few years ago. All the patients seen in this study presented with similar features to those seen elsewhere in patients with these syndromes.

Adolescent↗

Carcinoma of the thyroid at Harare histopathology laboratory (Zimbabwe).

The carcinoma of the thyroid gland seen at Harare Histopathology Laboratory (Zimbabwe) has been reviewed and analysed. There was a male to female ratio of 1:4. The commonest histological type of tumour was follicular carcinoma (70%). There were equal numbers of papillary and anaplastic types (14% each). Only two cases of medullary carcinoma were found, one of these being in a twelve-year-old female patient. The finding of a high occurance of follicular carcinoma is consistent with Zimbabwe being a country where endemic goitre is common.

Adolescent↗

Glial teratoma thought to be a lingual thyroid.

A case of a glial teratoma occurring in the tongue of a twelve week old male child is presented. This lesion was thought clinically to be a lingual thyroid. Histopathological examination revealed the true nature of the lesion. The mother had noticed the lesion since birth but only sought medical attention when the child developed difficulty in breathing. Teratomas in the head and neck region are uncommon and are commonly diagnosed wrongly as lingual thyroid. These lesions are usually benign.

Choristoma↗

Paediatric solid malignant tumours in Zimbabwe.

This paper presents solid childhood tumours seen in Zimbabwe. There were equal number of boys and girls under the age of fifteen years presenting with malignant tumours. Different tumours however showed differences in the sex frequencies. The commonest tumour seen was the Wilm's tumour with lymphomas as the second commonest tumour. Burkitt's lymphoma was very rare as were tumours of the central nervous system.

Adolescent↗

Schistosomal ova in a female breast.

A case of a female in which schistosomal ova were found in the breast is presented. The diagnosis was made on histological examination for a fibroadenoma. This case appears to be the first ever reported.

Adenofibroma↗

Intussusception due to inflammatory fibroid polyps of the ileum: a report of 12 cases from Africa.

Eleven cases of inflammatory fibroid polyp of the ileum from Malawi and 1 from Sierra Leone are described. All 12 patients presented with acute intestinal obstruction as a result of an intussusception caused by the polyp. The lesions are characterized by a variable proliferation of fibroblasts and small vessels which may involve the whole thickness of the bowel wall. Tissue mast cells and eosinophils were noted in the polyps. The aetiology of these lesions remains obscure but they appear to be reactive rather than neoplastic. The condition appears to occur more commonly in Malawi than in the United Kingdom or North America and is an important cause of small bowel obstruction in that part of Africa.

Adult↗

A review of autopsies at the University Teaching Hospital, Lusaka, 1975.

Findings in all clinical autopsies performed in 1975 are presented. The autopsy rate for all deaths was 17%, it was only 10% in childhood deaths, but rose to nearly 34% if stillbirths and neonatal deaths are excluded. The main causes of death are classified in major fields. In adults neoplasms were the commonest cause of death with acute infections and cardiac diseases following in order of importance. The value of the clinical autopsy is briefly discussed.

Adolescent↗