Biomedical subjects
Publications and source records attributed to N K Saied.
Two patients with atypical features of familial benign chronic pemphigus (FBCP) are presented herein. One patient had lesions limited to the anterior chest and the other had lesions localized to the lateral arms. Neither patient had prominent intertriginous involvement. These cases illustrate the protean manifestations of this disease.
Multiple cutaneous sebaceous neoplasms with or without keratocanthomas are associated with internal low-grade malignant neoplasms, usually of the gastrointestinal (GI) tract (Torre syndrome). We describe a 75-year-old man with multiple sebaceous adenomas, sebaceous epithellomas, and keratoacanthomas in association with multiple colonic polyps. In one polypoid lesion, an adenocarcinoma was noted histologically. Although GI tract carcinoma is clearly established with the Torre syndrome, the occurrence of multiple GI polyps has not been recognized to our knowledge.
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Pityriasis lichenoides is a notoriously difficult disease to treat. Three patients with this condition and a fourth with lymphomatoid papulosis have been successfully treated with doses of methotrexate once a week. Toxicity noted during the treatment periods has been minimal.
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