Identification and quantitative analysis of haptoglobin Johnson heterozygote.
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Blotting, Southern↗
Biomedical subjects
N Kadohno
Publications and source records attributed to N Kadohno.
[Pathophysiological background of transient hyperphosphatasemia].
We studied the relationship between 23 cases with transient hyperphosphatasemia (TH) and viral infection. Many of the patients appeared to be suffering from viral infection. Measurement of antibody in the titer revealed increases in antibody to Echo 22, Entero 71 and Coxsackie B5 in 20.0%, 11.1% and 11.1% of patients, respectively.
Alkaline Phosphatase↗
[Sex and age distribution of patients with macroamylasemia found in the daily isoenzyme analysis].
We studied distributions of sex and age for 102 patients with macroamylasemia found in routine isoenzyme analysis. This study was based on a questionnaire to promote understanding of the clinical significance of macroamylase. More than half of the physicians received our report evaluated the information on macroamylase in the questionnaire. Macroamylasemia found in this study consisted of IgA type immunoglobulin in 92% and mostly had high activities in the serum. The back-ground of these patients with macroamylasemia were 10 cases of hepato-biliary disease, 9 cases of diabetes mellitus, 8 cases of autoimmune disease and so on. The frequency of macroamylasemia in males was double than in females and age distribution was not significant in statistic analysis.
Adolescent↗
[Causes of anomalous patterns of haptoglobin using polyacrylamide gel electrophoresis].
We could observe several anomalous electrophoretic patterns of haptoglobin during serotype analysis. We classified these anomalous patterns of haptoglobin into two major classes. The first is the change of number of haptoglobin bands, and the second is the shift from the normal serotype patterns. The change of number of haptoglobin bands was caused by unsaturation of haptoglobin in binding with hemoglobin, mixing of different serotypes by blood transfusion or injection of haptoglobin and serotype variants of haptoglobin. The shift of haptoglobin PAGE pattern was occurred from a large amount of M-protein or lipoproteins in serum.
Electrophoresis, Polyacrylamide Gel↗