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N Kamimura

Publications and source records attributed to N Kamimura.

45 records · Page 3Linked to original sources
PubMed1982

[Application of the peripheral leukocyte cytofluorogram to diagnosis and treatment of hematopoietic tumors--with special reference to its effectiveness in malignant lymphoma].

In 1970 Adams and Kamentsky reported on a technique for classifying human peripheral leukocytes into three groups-lymphocytes, monocytes and granulocytes using supravital staining with a solution of acridine orange, and analyzing the resulting cell suspension with the Cytofluorogram. For the purpose of clinical application of flowcytometry, we investigated the clinical significance of this cytofluorogram of peripheral leukocytes. Cytofluorograms showed characteristic pattern in such hematopoietic malignancies as acute leukemias, chronic leukemias and malignant lymphomas, and turned out to be applicable to the diagnosis of these diseases. Especially in malignant lymphoma, cytofluorogram showed either normal or abnormal pattern. An abnormal cytofluorogram indicated poor prognosis, and an abnormal pattern of cytofluorogram became normalized after chemotherapy against lymphoma. Interestingly, those patients who showed in abnormal pattern relapsed in a short period, even when they were though diagnosed in remission. These data suggest that cytofluorograms are useful in diagnosing, predicting relapse and evaluating therapeutic effects for the treatment of malignant lymphoma. We hope that the analysis of cytofluorogram of peripheral leukocytes in lymphoma will provide a new benefit for further investigation of this disease.

Acridine Orange↗
PubMed1982

[A method to retain subcutaneously the catheter end connected to a new silicone reservoir in intraarterial infusion chemotherapy].

A method to retain subcutaneously the catheter end connected to a new silicone reservoir was developed in intraarterial infusion chemotherapy and applied to 12 patients. Its advantages were discussed. The method can be performed with only minor invasion; in addition, the retained catheter and reservoir needs no aseptic care. Accordingly, it liberates patients from restrictions in the daily life thus far experienced in the conventional method. The intraarterial infusion therapy can be done more easily and without hospitalization by this method. Thus, the method is considered to be quite beneficial in taking care of advanced cancer patients.

Aged↗