Acute myeloid leukemia with t(11;19)(q23;p13) developing in an adult T-cell leukemia patient treated with combined chemotherapy including etoposide.
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Acute Disease↗
Biomedical subjects
N Kanemura
Publications and source records attributed to N Kanemura.
Intrahepatic cholangiocarcinoma arising 10 years after the excision of congenital extrahepatic biliary dilation.
A 52-year-old woman was found to have a liver tumor during treatment for a liver abscess. The tumor was diagnosed as intrahepatic cholangiocarcinoma by closer examinations, including a percutaneous needle biopsy. Ten years previously, she had undergone excision of a choledochal cyst, with reconstruction by Roux-en-Y hepaticojejunostomy, as treatment for Todani's type Ia congenital biliary dilation, which had been confined only to the extrahepatic bile duct. The significant association between congenital biliary dilation and hepatobiliary malignancies is well known. Some patients have been reported to develop biliary cancer long after the excision of the entire extrahepatic bile duct and hepaticoenterostomy. However, in these patients, the development mostly took place in the remnant choledochal cyst, the anastomotic site, or in the dilated intrahepatic bile duct of Todani's type IV-A congenital biliary dilation. The development of intrahepatic cholangiocarcinoma after operation has not been reported previously in a patient with Todani's type I congenital biliary dilation. This case suggests that the entire biliary tree may have a high risk of field cancerization, even in extrahepatic congenital biliary dilation.
Bile Duct Diseases↗
[Multiple myeloma complicated by bilateral abducens nerve palsy due to a tumor in the clivus].
A 62-year-old woman was admitted to our hospital because of double vision. Bone marrow aspiration revealed normal cellularity with 21.6% atypical plasma cells. Immunoelectrophoresis revealed a monoclonal component of IgG kappa in the patient's serum. Coronal and sagittal cranial MRI images showed a tumor in the clivus behind the sella turcica. The patient was diagnosed as having multiple myeloma complicated by double vision due to compression of the bilateral abducens nerve by a plasmacytoma. VAD therapy consisting of vincristine, doxorubicin and dexamethasone, followed by irradiation of the clivus tumor achieved only a transient therapeutic effect, and the double vision and bone disease worsened. Cranial nerve palsy may be a significant complication of multiple myeloma.
Abducens Nerve Diseases↗
Three-dimensional measurement of rolling in tetraplegic patients.
OBJECTIVE: To investigate the differences between traumatic tetraplegic patients who can roll and those who cannot. DESIGN: Motion analysis using 3-dimensional measurement. SETTING: Rehabilitation centers in southwestern Japan. PARTICIPANTS: Nineteen male participants, all of whom had traumatic C6 complete injury. METHODS: We used an electromagnetic device to examine the degree of spinal movement in axial rotation during rolling (shifting from supine to side lying). This system (3-Space Win) measures the position and orientation of sensors in space. Two sensors were mounted on a subject over the spinous process of T1 and L5. RESULTS: The spinal rotation of patients who could not roll was significantly lower than that of patients who could roll. (The average rotation of non-rollers was 31.5+/-17.5 degrees, while the average rotation of rollers was 66.3+/-17.3degrees). In this study, there were no statistically significant differences in the members of the two groups in terms of age, height, weight or time after injury. CONCLUSION: Rolling requires greater and adequate flexibility in the back of tetraplegic patients.
Adult↗
Comparative microtensile bond strength and SEM analysis of bonding to wet and dry dentin.
PURPOSE: To compare bond strengths of resins to acid-etched wet vs. dry dentin. MATERIALS AND METHODS: Human third molars were bonded with One-Step (OS), Single Bond (SB) or Clearfil PhotoBond (PB) under control moist or air-dried (5 s air blast) conditions. Tensile bond strengths were tested using the microtensile bond testing method. Scanning electron microscopy was done to evaluate the quality and thickness of the hybrid layers following polishing and acid plus NaOCl-challenge. RESULTS: The tensile bond strengths of OS, SB and PB were significantly (P < 0.01) lower (8-19 MPa) to air-dried dentin than to moist dentin (39-50 MPa). No hybrid layers were seen in the air-dried specimens bonded with OS or SB, while relatively thin hybrid layers were produced by PB. In contrast, moist dentin produced high bond strengths with all bonding systems and created thicker, acid/NaOCl-resistant hybrid layers. These results support the predictions of a previously published morphologic model and offer a morphologic explanation for the differences in bond strengths between wet vs. dry bonds.
Acid Etching, Dental↗
Tensile bond strength to and SEM evaluation of ground and intact enamel surfaces.
OBJECTIVES: The aim of this study was to evaluate the bonding of four commercially available adhesive systems to ground and intact enamel surfaces. METHODS: Extracted human teeth were used to measure the microtensile bond strength to enamel and a field-emission scanning electron microscopy (FE-SEM) was used to observe the bonded interface and the effect of the surface conditioning of each material. Intact buccal enamel surfaces were cleansed with tooth paste using a rotary dental brush, and the ground enamel surfaces were prepared by reducing approximately 0.5 mm from the buccal enamel surfaces using a high-speed diamond bur. One-Step (OS, Bisco), Single Bond (SB, 3M), Clearfil Liner Bond II (LBII, Kuraray), and Tokuso Mac Bond II (MBII, Tokuso) were evaluated for their ability to bond to enamel. RESULTS: There was no significant difference in bond strengths between the materials when they were applied to ground enamel surfaces (p > 0.05). However, the bond strengths of the self-etching systems, LBII and MBII, had significantly lower bond strengths to intact enamel than the bonding systems OS and SB using phosphoric acid etching (p < 0.05). FE-SEM revealed that the etching pattern of self-etching primers was not deep enough to obtain good penetration of bonding resin when applied to intact enamel surfaces. CONCLUSIONS: Phosphoric acid etching produced good resin adhesion to ground and intact enamel. The self-etching/self-priming systems also produced good adhesion to ground enamel, but had lower bond strengths to intact enamel.
Acid Etching, Dental↗
Long-term durability of dentin bonds made with a self-etching primer, in vivo.
The long-term durability of bonds between adhesive resins and dentin is of significant importance for the longevity of bonded restorations. We carried out an in vivo one-year study to evaluate the durability of resin-dentin bonds in the oral cavity, as well as to test the hypothesis that the adhesive interface would show morphological changes in vivo over time. Very shallow saucer-shaped dentin cavities were prepared in 12 intact teeth of one Japanese monkey (Macaca fuscata) under general anesthesia. The cavities were restored with Clearfil Liner Bond II and Clearfil Photo Posterior resin composite. The teeth were extracted at three different times: immediately, and 180 and 360 days after placement of the restorations. One day after the monkey was killed, specimens of the three time periods were subjected to the micro-tensile bond test at a crosshead speed of 1 mm/min. The surfaces of the failed bonds were observed under a field emission scanning electron microscope (FE-SEM). Bond strength measurements in this study were successfully performed and were stable at approximately 19 MPa during the one-year testing. Scanning electron microscopic observations of the failed surfaces revealed, at the top of the hybrid layer and within the adhesive resin, porosity which increased over time. Long-term bonds can be assessed in vivo by the combined evaluation of the microtensile bond strength and SEM morphological examination of the adhesive interface.
Acid Etching, Dental↗
Effect of operator variability on dentin adhesion: students vs. dentists.
The purpose of this study was to evaluate the operator variability of two dentin bonding systems. Fourteen undergraduate students and ten dentists of different levels of clinical experience were selected. Tensile bond strengths between resin composite and bovine dentin using dentin adhesive systems (Clearfil Liner Bond II: LB II; Scotchbond Multi-Purpose: MP) bonding systems showed a large scatter among students and dentists. The dentists group demonstrated no statistically significant differences for mean bond strengths between LB II and MP. The student group recorded a statistically greater bond strength using LB II. The mean coefficient of variation of the dentists group showed no statistically significant difference between LB II and MP, however that of the students group was lower with LB II. When using MP, the dentist group demonstrated a lower coefficient of variation than that of the student group. In order to obtain optimal bonding performance, or when beginning the use of a new system, the operator should be aware of the technique sensitivity of some adhesive systems and sensitivity to operator variability.
Analysis of Variance↗
Possibility of independence in ADL (Activities of Daily Living) for patients with cervical spinal cord injuries--an evaluation based on the Zancolli Classification of Residual Arm Functions.
For patients with cervical spinal cord injuries to become independent in their ADL (Activities of Daily Living), residual arm function is very important. Also, age, sex, physical strengths, obesity, spasticity, pain, contracture and motivation are related. We investigated the possibility of independence in ADL for patients with cervical spinal cord injuries, carrying out our evaluation based on the Zancolli Classification of Residual Arm Functions. Zancolli classification C6BII is taken as the boundary level for ADL independence. Rehabilitation is not only controlled by the patients with cervical spinal cord injuries themselves but also by the ability of the rehabilitation staff. This implies that taking responsibility in rehabilitation important.
Activities of Daily Living↗
Adhesion between collagen depleted dentin and dentin adhesives.
PURPOSE: To determine the influence of sodium hypochlorite treatment of dentin on shear bond strength and morphology. MATERIALS AND METHODS: Shear bond strengths of several dentin bonding agents were compared following specific surface treatments that included manufacturer's directions, etching plus sodium hypochlorite, and sodium hypochlorite alone. The treated surfaces and interfaces between bonding materials and treated surfaces were observed using an FE-SEM. RESULTS: Acetone-containing systems yielded equivalent or higher shear bond strengths when sodium hypochlorite was used following etching, as compared with normal procedures. In these cases it is proposed that the adhesive interacts strongly with the treated surface, that contains a high mineral content.
Acetone↗
Shear bond strengths of a single-step bonding system to enamel and dentin.
An experimental primer was developed as a single-step bonding system for resin-modified glass ionomer cements (GIC). Efficacy of this primer on adhesion of resin-modified GICs and resin composite to enamel and dentin was evaluated by shear bond test and SEM observation. Good bond strengths to enamel were obtained (> 11 MPa), whereas significantly low bond strengths to dentin were obtained using a single coat of the primer. However, double-coating improved the bond strengths to dentin (> 8 MPa). SEM observations indicated that the primer functioned as a mild conditioner to remove the smear layer on enamel or dentin surfaces. A hybrid layer was observed at the cross-sectional view of the GIC/dentin interface. These findings suggested that good adhesion to enamel and dentin could be achieved using a single-step bonding system.
Bisphenol A-Glycidyl Methacrylate↗