Biomedical subjects

N Kasimov

Publications and source records attributed to N Kasimov.

10 recordsLinked to original sources

PubMed1990

[A telangiectatic clinical variant of mastocytosis].

Six cases of telangiectatic clinical variant of mastocytosis (TMV) are reported. Patients' age varied from 33 to 62, there were 2 men and 4 women. A number of clinical features of TMV were detected in the course of follow-up: a generalized type of the skin process; abundant maculopapular eruptions colored brownish, sometimes with a cyanotic shade, liable to fuse and form diffuse foci of involvement; development of telangiectasias on the surface of these eruptions; symptoms of elevated blood histamin levels, i.e. regular blood congestion, enhanced itching, tachycardia, gastrointestinal events, etc.; systemic mastocytosis (3 of the 6 patients developed lymphadenopathy and hepatomegaly). The detected features of the condition permit considering TMV as an individual clinical variety of mastocytosis.

Adrenal Cortex Hormones↗

PubMed1989

[Ashy dermatosis].

Five patients with ashy dermatitis are described, aged 6 to 14, one boy and four girls. The process is characterized by dirty grayish or ash-gray-colored maculae on the skin of the trunk and limbs. These maculae do not tend to fuse, nor exfoliate; they are not associated with any subjective sensations. Thorough examinations have not revealed any osteomuscular or visceral abnormalities. The disease runs a benign course, and only the cosmetic defect worries the patients.

Adolescent↗

PubMed1989

[The clinical picture and therapy of nodular mastocytosis].

The authors review the literature data on and describe 6 cases of nodular mastocytosis presenting as multiple blending nodes. The patients (2 girls and 4 boys aged under 4) have developed a disseminated process with multiple nodes up to 3.0-3.5 cm in diameter colored brownish or yellowish, mostly with a smooth surface, localized on the hairy part of the head, trunk, and limbs. Some nodes blended to form larger foci of lesions, particularly on the back and in large skin folds. In 5 patients the diagnosis has been confirmed histologically. No visceral or systemic abnormalities have been revealed. Enlarged (pea-size) inguinal and cubital lymph nodes have been detected in one child. Zaditen therapy has been fairly effective.

Child, Preschool↗

PubMed1987

[Morphology of mastocytosis].

Histochemical and electron-microscopic studies of skin biopsy specimens from 65 patients with mastocytosis have enabled the authors to classify the various mastocytoses (on the basis of infiltrate topography and structural features of mast cells) into macular, pustular, and nodular varieties of cutaneous mastocytosis (urticaria pigmentosa) and mastocytoma. No differences in mast cell structure were detected between cutaneous and systemic mastocytoses. Electron microscopically, mast cells in both appeared normal, with a predominance of granules having a fine-grained or homogeneous matrix and a small number of lamellar structures. In mastocytomas, on the other hand, ultrastructural changes and considerable degranulation were observed in the mast cells.

Adolescent↗

PubMed1986